Showing 7371-7380 of 10620 results for "".
- First Patient Dosed with GPX4 Modulator Targeting Pathologic Senescent Cellshttps://reachmd.com/news/first-patient-dosed-with-gpx4-modulator-targeting-pathologic-senescent-cells/2475369/The first patient has been dosed with the lead drug candidate RLS-1496 in a single-center, ascending-dose, randomized, double-blind, vehicle-controlled trial, Rubedo Life Sciences, Inc., announced in a press release. The study marks the first time a glutathio
- Prognostic Factors in Diffuse Glioma: The Limited Role of Tumor-Related Epilepsyhttps://reachmd.com/news/prognostic-factors-in-diffuse-glioma-the-limited-role-of-tumor-related-epilepsy/2474795/Advanced studies in oncology and neurology are reshaping the prognostic assessment methodology for diffuse glioma. While tumor-related epilepsy is a frequent occurrence, its presence alone is not a predictor of survival or disease progression. Clinicians are
- Genomic Risk Assessment: Predicting the Progression of Multiple Myelomahttps://reachmd.com/news/genomic-risk-assessment-predicting-the-progression-of-multiple-myeloma/2474794/Recent studies have led to the creation of a genomic score based on comprehensive DNA mutation analysis, anticipating the progression from benign precursor states to malignant multiple myeloma. This innovation not only reveals the genet
- Liver Metabolism: The Role of PPP1R3B in Energy Storage and Metabolic Disease Riskhttps://reachmd.com/news/liver-metabolism-the-role-of-ppp1r3b-in-energy-storage-and-metabolic-disease-risk/2474736/The liver’s ability to store energy is governed by intricate mechanisms. PPP1R3B serves as a scaffold for protein phosphatase 1, aiding glycogen synthesis. Conversely, reduced PPP1R3B function correlates with triglyceride accumulation, escalating liver fat levels.<
- Residual Inflammation and Its Systemic Implications in Psoriasis Patientshttps://reachmd.com/news/residual-inflammation-and-its-systemic-implications-in-psoriasis-patients/2474776/While biologic therapies greatly improve skin symptoms, psoriasis patients often endure residual systemic inflammation, which can lead to serious comorbidities like obesity, cardiovascular disease, and fatty liver disease. Extensive clinical ins
- Alzheimer's Disease: Investigating a New Therapeutic Approach to Protein Toxicity and Memory Improvementhttps://reachmd.com/news/alzheimers-disease-investigating-a-new-therapeutic-approach-to-protein-toxicity-and-memory-improvement/2474775/Recent preclinical studies in mouse models of Alzheimer’s disease have explored a novel drug candidate that not only reduces toxic protein levels in the brain but also enhances memory performance by increasing protective protein production.
- Preoperative Evaluation: Assessing Alcohol Consumption in Older Patientshttps://reachmd.com/news/preoperative-evaluation-assessing-alcohol-consumption-in-older-patients/2474781/In clinical practice, fields such as surgery and geriatrics increasingly acknowledge the value of thorough preoperative assessments, especially for older adults. Among the many risk factors considered, evaluating alcohol consumption patterns has emerged as a crucia
- Single-Stage Revision and Prosthetic Joint Infection Management in Hip Arthroplastyhttps://reachmd.com/news/single-stage-revision-and-prosthetic-joint-infection-management-in-hip-arthroplasty/2474784/Overview and Significance Recent advancements in surgical technique and infectious disease management have brought single-stage revision to the forefront in the treatment of prosthetic joint infections (PJIs). This progressi
- Dr. David Shafer Explains Benefits of Breast Augmentation Visualization Toolhttps://reachmd.com/news/dr-david-shafer-explains-benefits-of-breast-augmentation-visualization-tool/2475364/The Natrelle Breast Visualizer, powered by Crisalix, allows patients to preview their potential breast augmentation results in just a few clicks. Modern Aesthetics spoke with double board-certified plastic surgeon David Shafer, MD, FACS, about the challenges this technology help
- Pre-Infection Cardiorespiratory Fitness and Long COVID Outcomeshttps://reachmd.com/news/pre-infection-cardiorespiratory-fitness-and-long-covid-outcomes/2474754/Emerging research is redefining how clinicians assess long COVID risk by placing new emphasis on pre-infection cardiorespiratory fitness. Evidence now shows that individuals with lower fitness levels before contracting COVID-19 are more likely to develop persistent p