Showing 9081-9090 of 19239 results for "".
- IL‑2–Armored FLT3 CAR‑γδT Cells: Preclinical Efficacy and Translational Signalshttps://reachmd.com/news/il2armored-flt3-cart-cells-preclinical-efficacy-and-translational-signals/2486036/Investigators report a preclinical evaluation of FLT3-targeted CAR-γδT cells “armored” to co-express IL-2 or IL-7 in acute myeloid leukemia (AML) models. The study describes three engineered prod
- Comparative Outcomes of Fluticasone‑Based vs Budesonide Dual Inhalers in COPDhttps://reachmd.com/news/comparative-outcomes-of-fluticasonebased-vs-budesonide-dual-inhalers-in-copd/2486037/Investigators reported comparative outcomes among US adults aged 40 years or older with chronic obstructive pulmonary disease (COPD) who initiated one of three inhaled corticosteroid–long-acting β-agonist (ICS–LABA) single-inhaler products in
- Intranasal Dexmedetomidine Combined with Oral Chloral Hydrate or Midazolam: RCT Resultshttps://reachmd.com/news/intranasal-dexmedetomidine-combined-with-oral-chloral-hydrate-or-midazolam-rct-results/2486004/In a randomized head-to-head outpatient study of pediatric procedural sedation regimens, Li and colleagues evaluated intranasal dexmedetomidine paired with either ora
- First-week Hyperglycemia in Extremely Preterm Infantshttps://reachmd.com/news/first-week-hyperglycemia-in-extremely-preterm-infants-propensity-matched-cohort-findings/2486010/In extremely preterm infants, does first-week neonatal hyperglycemia identify a group with different short-term respiratory and ophthalmologic outcomes? Investigators at a single NICU reported a
- AMPAR PET Imaging Links Ketamine to Rapid Antidepressant Responsehttps://reachmd.com/news/ampar-pet-imaging-links-ketamine-to-rapid-antidepressant-response/2486011/Investigators used PET imaging to visualize cell-surface AMPA receptor (AMPAR) dynamics in people with treatment-resistant depression in relation to ketamine’s antidepressant effects, describing region-specific receptor changes associated with symptom improvement.
- Integrated MALDI‑TOF MS and WGS in a Prolonged ICU Pseudomonas Outbreakhttps://reachmd.com/news/integrated-malditof-ms-and-wgs-in-a-prolonged-icu-pseudomonas-outbreak/2486016/In a prolonged intensive care unit (ICU) outbreak investigation of Pseudomonas aeruginosa, authors report using an integrated laboratory approach that combined phenotypic antimicrobial testing,
- Gut Microbiome and Checkpoint Immunotherapy: Reporting Recent Synthesishttps://reachmd.com/news/gut-microbiome-and-checkpoint-immunotherapy-reporting-recent-synthesis/2485990/An integrated review examined how gut microbial communities relate to variable outcomes with PD-1/PD-L1 checkpoi
- 4‑Chlorothienopyridine Caps Yield Potent, Selective HDAC Inhibitors — Preclinical Reporthttps://reachmd.com/news/4chlorothienopyridine-caps-yield-potent-selective-hdac-inhibitors-preclinical-report/2486007/Investigators report a series of hydroxamic-acid HDAC inhibitors built around substituted 4-chlorothieno[2,3-b]pyridine cap groups, spanning series 6a–c and 7a–c (aliphatic linkers) and 9a–c (cinnamic linkers). Each combines a cap, spacer, and hydroxamic acid zinc-binding motif in the final
- EEG Time‑Frequency Images Predict SSRI and rTMS Responsehttps://reachmd.com/news/eeg-timefrequency-images-predict-ssri-and-rtms-response/2485996/Authors describe a pretreatment resting-EEG deep-learning pipeline that converts baseline recordings into time–frequency EEG images and evaluates models that classify SSRI and rTMS responder versus non-responder status. Performance is presented at both the image lev
- Human hIEC Model Reports High Accuracy for Detecting Drug-Induced Intestinal Barrier Damagehttps://reachmd.com/news/human-hiec-model-reports-high-accuracy-for-detecting-drug-induced-intestinal-barrier-damage/2485995/The report describes a stem-cell–derived hIEC model designed to detect drug-induced intestinal barrier impairment by recreating key aspects of