Showing 4991-5000 of 21485 results for "".
- Dronabinol Reduced PTSD Nightmares in 10-Week Trialhttps://reachmd.com/news/dronabinol-ptsd-nightmares-trial/2488042/Key Takeaways In patients with post-traumatic stress disorder (PTSD) and frequent, intense nightmares, bedtime dronabinol reduced nightmare burden more than placebo in a placebo-controlled trial. More than one-third of dronabinol-treated patients reported complete di
- Understanding Buprenorphine First-Prescription Abandonmenthttps://reachmd.com/news/buprenorphine-first-prescription-abandonment/2488040/Key Takeaways Among insured adults with opioid use disorder receiving a first buprenorphine prescription, 25.8% of prescriptions were abandoned. Annual abandonment of first buprenorphine prescriptions rose from 19% in 2020 to 37% in 2024, and the increase was statistically si
- AI Screening for Referable AMD Shows 90% Sensitivityhttps://reachmd.com/news/ai-screening-referable-amd-sensitivity/2488037/Key Takeaways In adults older than 50 without a prior AMD diagnosis who were screened in New York City primary care and ophthalmology clinics, iPredict-AMD identified referable AMD with strong discrimination in this study. Most participants with disease beyond early
- FDA Approves Tudriqev Plus Nivolumab for Advanced Melanomahttps://reachmd.com/news/fda-approves-tudriqev-plus-nivolumab-for-advanced-melanoma/2488043/The FDA has granted accelerated approval to Tudriqev (vusolimogene oderparepvec-wtpg; Replimune, Inc.) in combination with nivolumab for adults with unresectable advanced cutaneous melanoma whose disease progressed on a programmed death receptor-1 (PD-1)–blocking antibody-based regimen, according
- EQA Data Show Better Kidney Biomarker Precision Over 15 Yearshttps://reachmd.com/news/eqa-data-show-better-kidney-biomarker-precision-over-15-years/2488030/Key Takeaways A large Brazilian External Quality Assessment (EQA) program tracked serum creatinine, urinary creatinine, urinary albumin, and total urinary protein over 15 years and showed improving precision and adequacy. Amidinohydrolase/oxidase methods appeared to
- Cretostimogene Demonstrates Promising Activity in High-Risk BCG-Unresponsive Bladder Cancerhttps://reachmd.com/news/cretostimogene-demonstrates-promising-activity-in-high-risk-bcg-unresponsive-bladder-cancer/2488022/Key Takeaways In the phase 3 BOND-003 Cohort C trial, intravesical cretostimogene produced a complete response in 75% of patients with high-risk, BCG-unresponsive non-muscle-invasive bladder cancer (NMIBC) with carcinoma in situ. After a median follow-up of 25
- Weight May Alter Pediatric Asthma Drug Responsehttps://reachmd.com/news/weight-may-alter-pediatric-asthma-drug-response/2488024/Key Takeaways In a systematic review of pediatric asthma treatment by weight status, inhaled corticosteroid-centered advantages appeared less consistent in children with overweight or obesity than in normal-weight peers. At GINA step 2, heavier children often showed
- Tumor Acidity Linked to PARP Resistance in Ovarian Cancerhttps://reachmd.com/news/tumor-acidity-linked-to-parp-resistance-in-ovarian-cancer/2488026/Key Takeaways In ovarian cancer cells and preclinical ovarian cancer models, acidic conditions were associated with significantly lower sensitivity to PARP inhibitors. The reported resistance mechanism linked acidity to ERK-p300-PARP1 signaling, PARP1 acetylation, an
- COPD Facial Wrinkles Not Linked to Disease Severity in Thai Studyhttps://reachmd.com/news/copd-facial-wrinkles-not-linked-to-disease-severity-in-thai-study/2488032/Key Takeaways In Thai patients with spirometry-confirmed COPD at a Bangkok tertiary center, adjusted analyses did not identify a significant association between facial wrinkle severity and COPD-related measures such as FEV1 % predicted, cumulative smoking exposure, or smoking
- National Study Finds Higher Follow-Up Colonoscopy Rates After Positive mt-sDNA Than FIThttps://reachmd.com/news/national-study-finds-higher-follow-up-colonoscopy-rates-after-positive-mt-sdna-than-fit/2488021/Key Takeaways In a national retrospective study, patients with a positive multitarget stool DNA (mt-sDNA) test were more likely to complete recommended follow-up colonoscopy within one year than patients with a positive fecal immunochemical test (FIT) or fecal occult blood test