Showing 3931-3940 of 21451 results for "".
- BCG Plus Mitomycin Fails to Improve DFS in ANZUP 1301https://reachmd.com/news/bcg-mitomycin-dfs-anzup-1301/2487173/Key Takeaways BCG plus mitomycin did not show disease-free survival superiority over BCG alone in this randomized phase 3 trial. Recurrence and progression events were numerically lower in the combination arm, and other secondary counts were reported f
- CASCARA Phase II Tests Cabazitaxel-Carboplatin-Abiraterone In mCSPChttps://reachmd.com/news/cascara-phase-ii-tests-cabazitaxel-carboplatin-abiraterone-in-mcspc/2487152/Key Takeaways Twelve-month PSA progression-free survival was 84.6%, and 12-month overall survival was 94.8%. Complete PSA and objective responses were reported, while HRR-mutated patients had numerically fewer complete PSA responses and shorter progres
- Azithromycin Fails to Improve Preschool Wheeze in ED Trialhttps://reachmd.com/news/azithromycin-fails-to-improve-preschool-wheeze-in-ed-trial/2487149/Key Takeaways Azithromycin was not associated with lower 5-day wheezing symptom scores than placebo. This pattern was observed in both the pathogenic-bacteria positive and pathogenic-bacteria negative cohorts. Bacterial clearance was higher wi
- Medicaid Expansion and Optimal Starts for Incident Kidney Failurehttps://reachmd.com/news/medicaid-expansion-and-optimal-starts-for-incident-kidney-failure/2487058/Key Takeaways Optimal starts continued to rise in expansion states after 2014, while the adjusted pattern declined in nonexpansion states. Most of the widening gap was associated with stronger growth in home dialysis starts, whereas transplant and in-c
- High-Intensity Exercise and Physical Activity Maintenance in Rheumatoid Arthritishttps://reachmd.com/news/high-intensity-exercise-activity-maintenance-ra/2487042/Key Takeaways The supervised program was associated with more accelerometer-measured ambulatory vigorous physical activity at 12 months than the comparison approach. Self-reported bicycling was more likely at 6 months and self-reported strength exercis
- Comparative Predictive Value Of Immunotherapy Biomarkers Across Cancershttps://reachmd.com/news/comparative-predictive-value-of-immunotherapy-biomarkers-across-cancers/2487024/Key Takeaways ctDNA ranked highest for sensitivity and overall discriminative ability in the pooled comparison. PD-L1 performance depended on threshold, with higher cutoffs aligning with specificity and lower cutoffs aligning with sensitivity.
- Pharmacist-Led Stewardship Improved HAP and VAP Prescribing in Trialhttps://reachmd.com/news/pharmacist-led-stewardship-improved-hap-and-vap-prescribing-in-trial/2486995/Key Takeaways Higher day-3 prescribing appropriateness was observed with pharmacist-led antimicrobial stewardship than with standard care. Higher clinical cure and lower antimicrobial exposure, readmission, and antimicrobial-related adverse events were
- Prophylactic Acetaminophen Did Not Improve PDA Outcomeshttps://reachmd.com/news/prophylactic-acetaminophen-did-not-improve-pda-outcomes/2486994/Key Takeaways Prophylactic acetaminophen was not associated with a higher rate of survival without severe morbidity at 36 weeks' postmenstrual age than placebo. Day-7 ductus arteriosus closure was more frequent with acetaminophen in the exploratory ana
- Positive Affect Treatment Improves Clinical Status in Low Positive Affecthttps://reachmd.com/news/positive-affect-treatment-improves-clinical-status-in-low-positive-affect/2487001/Key Takeaways Positive Affect Treatment was associated with better multivariate clinical status than the comparison psychotherapy. A between-group advantage was reported at 1 month and appeared to reflect depression and anxiety symptom change more than
- Comparative Efficacy of Single-Inhaler Triple Therapies in COPDhttps://reachmd.com/news/comparative-efficacy-of-single-inhaler-triple-therapies-in-copd/2486960/Key Takeaways Fluticasone furoate/vilanterol/umeclidinium was the regimen specifically reported as having significant trough FEV1 advantages in the network comparison. Fluticasone furoate/vilanterol/umeclidinium, budesonide/formoterol/glycopyrronium, a