Showing 3921-3930 of 21451 results for "".
- Routine Gastric Residual Checks In Critically Ill Childrenhttps://reachmd.com/news/gastric-residual-checks-critically-ill-children/2487476/Key Takeaways No routine assessment was noninferior for survival and days free of mechanical ventilation at 30 days in the randomized comparison. Early nutrition delivery was modestly higher, and time with no enteral feed was shorter, in the group with
- Obexelimab Lowers Flare Risk in IgG4-Related Diseasehttps://reachmd.com/news/obexelimab-lowers-flare-risk-in-igg4-related-disease/2487459/Key Takeaways Weekly obexelimab was associated with a longer time to first flare requiring rescue therapy and a lower observed flare risk than placebo. By week 52, complete remission was more common and cumulative rescue glucocorticoid use was lower wi
- 4% Tetrasodium EDTA Lowers CVAD Complications in ICU Trialhttps://reachmd.com/news/tetrasodium-edta-cvad-complications/2487397/Key Takeaways The primary composite outcome occurred less often during t-EDTA periods than during control periods. In prespecified analyses of the primary outcome components, only catheter occlusion requiring alteplase use showed a significant between-
- Postoperative Nivolumab Does Not Improve DFS in Resected NSCLChttps://reachmd.com/news/postoperative-nivolumab-does-not-improve-dfs-in-resected-nsclc/2487358/Key Takeaways Adjuvant nivolumab was not associated with a significant disease-free survival benefit compared with observation in patients with resected NSCLC who completed standard adjuvant therapy. No significant disease-free survival benefit was obs
- COLOR III Short-Term Outcomes: taTME vs Laparoscopic TMEhttps://reachmd.com/news/color-iii-tatme-laparoscopic-tme/2487343/Key Takeaways taTME was associated with lower conversion than laparoscopic TME in this short-term comparison. 90-day morbidity, anastomotic leakage, and macroscopically complete resection appeared similar between groups. In the
- Integrase Versus Protease Inhibitors In Advanced HIV Diseasehttps://reachmd.com/news/integrase-versus-protease-inhibitors-in-advanced-hiv-disease/2487284/Key Takeaways Across planned analyses, the bictegravir-based regimen matched the comparator on the primary composite endpoint and met the trial's noninferiority threshold. Grade 2 or higher drug-related adverse events were less frequent with bictegravi
- Baseline Imaging in ESCAPE-MeVO Linked To 90-Day Outcomeshttps://reachmd.com/news/baseline-imaging-in-escape-mevo-linked-to-90-day-outcomes/2487285/Key Takeaways Baseline head CT, CTA, and CT perfusion findings were reviewed in a central blinded core laboratory analysis of ESCAPE-MeVO participants. CTA collateral status was associated with 90-day modified Rankin Scale outcome, and the abstract des
- Budesonide Glycopyrronium Formoterol Improved Lung Function in Phase 3 Asthma Trialshttps://reachmd.com/news/budesonide-glycopyrronium-formoterol-improved-lung-function-in-phase-3-asthma-trials/2487270/Key Takeaways Multiplicity-adjusted primary lung-function endpoints were met in both studies, and lung function favored budesonide-glycopyrronium-formoterol 320/28.8/10 mcg across comparisons. Pooled severe exacerbation rates were lower versus the comb
- Guselkumab Shows Week 24 Efficacy After TNF Inhibitor Failure in PsAhttps://reachmd.com/news/guselkumab-shows-week-24-efficacy-after-tnf-inhibitor-failure-in-psa/2487212/Key Takeaways Both guselkumab schedules were associated with higher week 24 responses than placebo across the reported efficacy endpoints. Week 24 efficacy appeared similar between the every-4-week and every-8-week guselkumab regimens. Adverse
- CBT After Esketamine in Major Depression and Suicidal Ideationhttps://reachmd.com/news/cbt-after-esketamine-in-major-depression-and-suicidal-ideation/2487211/Key Takeaways The randomized comparison met feasibility criteria, reaching 80% of targeted enrollment and 70% retention through the study endpoint. Over 18 weeks, several clinician- and patient-rated measures favored the CBT group over treatment as usu