Showing 4801-4810 of 21478 results for "".
- Survey Finds Topical Corticosteroid Concerns Affect Use and Patient-Clinician Discussionshttps://reachmd.com/news/survey-finds-topical-corticosteroid-concerns-affect-use-and-patient-clinician-discussions/2488682/Concerns about adverse effects were associated with less frequent use of prescribed topical corticosteroids (TCS) among adults and caregivers of children with inflammatory skin conditions, according to survey findings presented at the 2026 Fall Clinical Dermatology Conference. Tina Bhutani
- Difamilast Ointment Shows Week 4 Benefits in Pediatric and Adult Atopic Dermatitis Trialshttps://reachmd.com/news/difamilast-ointment-shows-week-4-benefits-in-pediatric-and-adult-atopic-dermatitis-trials/2488681/Difamilast 1% ointment was associated with higher rates of Investigator’s Global Assessment (IGA) success than vehicle at week 4 in separate phase 3 studies involving adults and children with atopic dermatitis (AD), according to an integrated review presented at the 2026 Fall Clinical Dermatology
- Hyperpigmentation Review Examines Treatment Strategies and Evidence Gaps in Skin of Colorhttps://reachmd.com/news/hyperpigmentation-review-examines-treatment-strategies-and-evidence-gaps-in-skin-of-color/2488677/A literature review presented at the 2026 Fall Clinical Dermatology Conference examined mechanisms and treatment strategies for hyperpigmentation disorders, emphasizing persistent gaps in evidence involving patients with skin of color. Susan Taylor, MD, of the University of Pennsylvania, a
- Comparison Examines GEP Performance Against Melanoma SLNB Risk Thresholdshttps://reachmd.com/news/comparison-examines-gep-performance-against-melanoma-slnb-risk-thresholds/2488674/A comparison of two prospective studies evaluating gene expression profiling (GEP) tests combined with clinicopathologic factors found differences in their ability to identify patients with cutaneous melanoma at low risk for sentinel lymph node (SLN) positivity.1
- Pre-Arrival Hypothermia in Pediatric TBI Linked to Higher Mortalityhttps://reachmd.com/news/pre-arrival-hypothermia-in-pediatric-tbi-linked-to-higher-mortality/2488666/Key Takeaways Among 171 children with traumatic brain injury (TBI) admitted to the intensive care unit of a level 1 pediatric trauma center, 40.4% experienced hypothermia before trauma center arrival. Mortality was significantly higher among children with prehospital
- Switching From Dupilumab to Upadacitinib Associated With No Skin Flares in Atopic Dermatitis Analysishttps://reachmd.com/news/switching-from-dupilumab-to-upadacitinib-associated-with-few-flares-in-atopic-dermatitis-analysis/2488672/Patients with moderate-to-severe atopic dermatitis (AD) who switched from dupilumab to upadacitinib monotherapy following inadequate treatment response experienced no observed skin lesion flares and infrequent itch flares over 16 weeks, according to a post hoc analysis pres
- TOGETHER-PsO: Combination Therapy Shows Expanded Molecular Response by Week 12https://reachmd.com/news/together-pso-combination-therapy-shows-expanded-molecular-response-by-week-12/2488671/Eli Lilly and Company announced Phase 3 data from the TOGETHER-PsO trial indicating broader immune and metabolic biomarker changes with concomitant ixekizumab (Taltz) and tirzepatide (Zepbound) compared with ixekizumab alone in adults with moderate-to-severe plaque psoriasis and obesity or overwe
- Vitamin B12 Deficiency Linked to Higher Fracture Hazardhttps://reachmd.com/news/vitamin-b12-deficiency-linked-to-higher-fracture-hazard/2488654/Key Takeaways Among adults aged at least 50 years who underwent vitamin B12 testing in a multicenter electronic-record cohort, deficiency was associated with higher subsequent incident fracture hazard than normal concentrations. The association persisted in a later s
- Glomerular Allele-Specific Expression Linked to Kidney Outcomeshttps://reachmd.com/news/glomerular-allele-specific-expression-linked-to-kidney-outcomes/2488656/Key Takeaways In the Nephrotic Syndrome Study Network (NEPTUNE) biopsy cohort of patients with proteinuric kidney disease, glomerular allelic imbalance exceeded tubulointerstitial imbalance. Relative imbalance between kidney compartments was greater in proteinuric di
- FDA Solid Tumor Approvals Shift Toward Surrogate Endpointshttps://reachmd.com/news/fda-solid-tumor-approvals-shift-toward-surrogate-endpoints/2488657/Key Takeaways In FDA adult solid tumor indication approvals, overall survival became less common as a primary endpoint. Surrogate endpoints became more common, and response rate overtook progression-free survival as the leading surrogate. Single-arm pivotal