Showing 3641-3650 of 20434 results for "".
- Azithromycin Fails to Improve Preschool Wheeze in ED Trialhttps://reachmd.com/news/azithromycin-fails-to-improve-preschool-wheeze-in-ed-trial/2487149/Key Takeaways Azithromycin was not associated with lower 5-day wheezing symptom scores than placebo. This pattern was observed in both the pathogenic-bacteria positive and pathogenic-bacteria negative cohorts. Bacterial clearance was higher wi
- Medicaid Expansion and Optimal Starts for Incident Kidney Failurehttps://reachmd.com/news/medicaid-expansion-and-optimal-starts-for-incident-kidney-failure/2487058/Key Takeaways Optimal starts continued to rise in expansion states after 2014, while the adjusted pattern declined in nonexpansion states. Most of the widening gap was associated with stronger growth in home dialysis starts, whereas transplant and in-c
- High-Intensity Exercise and Physical Activity Maintenance in Rheumatoid Arthritishttps://reachmd.com/news/high-intensity-exercise-activity-maintenance-ra/2487042/Key Takeaways The supervised program was associated with more accelerometer-measured ambulatory vigorous physical activity at 12 months than the comparison approach. Self-reported bicycling was more likely at 6 months and self-reported strength exercis
- Comparative Predictive Value Of Immunotherapy Biomarkers Across Cancershttps://reachmd.com/news/comparative-predictive-value-of-immunotherapy-biomarkers-across-cancers/2487024/Key Takeaways ctDNA ranked highest for sensitivity and overall discriminative ability in the pooled comparison. PD-L1 performance depended on threshold, with higher cutoffs aligning with specificity and lower cutoffs aligning with sensitivity.
- Positive Affect Treatment Improves Clinical Status in Low Positive Affecthttps://reachmd.com/news/positive-affect-treatment-improves-clinical-status-in-low-positive-affect/2487001/Key Takeaways Positive Affect Treatment was associated with better multivariate clinical status than the comparison psychotherapy. A between-group advantage was reported at 1 month and appeared to reflect depression and anxiety symptom change more than
- Prophylactic Acetaminophen Did Not Improve PDA Outcomeshttps://reachmd.com/news/prophylactic-acetaminophen-did-not-improve-pda-outcomes/2486994/Key Takeaways Prophylactic acetaminophen was not associated with a higher rate of survival without severe morbidity at 36 weeks' postmenstrual age than placebo. Day-7 ductus arteriosus closure was more frequent with acetaminophen in the exploratory ana
- Pharmacist-Led Stewardship Improved HAP and VAP Prescribing in Trialhttps://reachmd.com/news/pharmacist-led-stewardship-improved-hap-and-vap-prescribing-in-trial/2486995/Key Takeaways Higher day-3 prescribing appropriateness was observed with pharmacist-led antimicrobial stewardship than with standard care. Higher clinical cure and lower antimicrobial exposure, readmission, and antimicrobial-related adverse events were
- Spot Sepsis Study Reports Improved Referral Prediction In Febrile Childrenhttps://reachmd.com/news/spot-sepsis-study-reports-improved-referral-prediction-in-febrile-children/2486970/Key Takeaways Models combining simple clinical signs with pulse oximetry or sTREM1 were reported to recognize more high-risk children than current WHO danger signs. The newer approaches were projected to lower referral burden substantially compared wit
- Comparative Efficacy of Single-Inhaler Triple Therapies in COPDhttps://reachmd.com/news/comparative-efficacy-of-single-inhaler-triple-therapies-in-copd/2486960/Key Takeaways Fluticasone furoate/vilanterol/umeclidinium was the regimen specifically reported as having significant trough FEV1 advantages in the network comparison. Fluticasone furoate/vilanterol/umeclidinium, budesonide/formoterol/glycopyrronium, a
- Secukinumab Falls Short in Phase III SELUNE Trialhttps://reachmd.com/news/secukinumab-phase-iii-selune-lupus-nephritis/2486924/Key Takeaways In SELUNE, complete renal response at week 52 was lower with secukinumab than with placebo in lupus nephritis. Adverse event rates were broadly similar, no new or unexpected safety signals emerged overall. In the