Showing 3621-3630 of 20433 results for "".
- Depemokimab Indirect Comparison Shows Similar Asthma Exacerbation Reductionhttps://reachmd.com/news/depemokimab-indirect-comparison-shows-similar-asthma-exacerbation-reduction/2487563/Key Takeaways In the fully adjusted model, depemokimab was associated with lower annualized exacerbation rates than placebo, while adjusted comparisons with other biologics were not statistically significant. Exacerbation estimates came from 17 trials
- Aglatimagene Besadenovec Plus Radiotherapy Improves Disease-Free Survivalhttps://reachmd.com/news/aglatimagene-besadenovec-plus-radiotherapy-improves-disease-free-survival/2487564/Key Takeaways Median disease-free survival was not reached with aglatimagene plus valacyclovir and was 86.1 months with placebo plus valacyclovir. The phase 3 randomized, double-blind, placebo-controlled trial enrolled 745 men across 51 centres in the
- Triple Low-Dose Antihypertensive Pill After Intracerebral Hemorrhagehttps://reachmd.com/news/triple-low-dose-antihypertensive-pill-intracerebral-hemorrhage/2487533/Key Takeaways Recurrent stroke was less frequent with the fixed low-dose triple pill than with placebo during follow-up. Mean systolic blood pressure during follow-up and major cardiovascular events were lower in the triple-pill group. Serious
- Phase 2a Trial of Intrapleural LTI 01 in Pleural Infectionhttps://reachmd.com/news/phase-2a-intrapleural-lti-01-pleural-infection/2487539/Key Takeaways Overall treatment failure within 7 days was not significantly different between LTI-01 and placebo. Predetermined sensitivity analyses showed efficacy trends in the 400,000-U group, while pleural opacification changes were strongest at 80
- C-TRACT Trial: Endovascular Therapy Lowers PTS Severity, Improves QOLhttps://reachmd.com/news/c-tract-endovascular-pts-severity-qol/2487536/Key Takeaways Six-month post-thrombotic syndrome severity was lower with endovascular therapy plus standard care than with standard care alone. Patient-reported quality of life was better with the endovascular strategy on both VEINES-QOL and SF-36.
- Text Messaging and FIT Completion in a Quality Improvement Trialhttps://reachmd.com/news/text-fit-completion-quality-improvement/2487515/Key Takeaways FIT completion within 21 days was higher in the text group than in the telephone group. Adults with new FIT orders at eight Brooklyn FQHCs were randomized 1:1 to three one-way texts on days 2, 5, and 8 or one nurse-led day-8 call.
- Analysis Shows Long-Term Cost Impact of Psoriasis and Psoriatic Arthritishttps://reachmd.com/news/analysis-highlights-long-term-cost-impact-of-psoriasis-and-psoriatic-arthritis/2487486/New research published in Dermatology and Therapy suggests the economic burden associated with psoriasis and psoriatic arthritis extends far beyond the diseases themselves and may reach hundreds of billions of dollars over a lifetime. Psoriatic Disease Comorbidities Drive Signifi
- Intramuscular Sedatives for Methamphetamine Agitation in the EDhttps://reachmd.com/news/intramuscular-sedatives-for-methamphetamine-agitation-in-the-ed/2487500/Key Takeaways Droperidol, olanzapine, and midazolam were similarly effective, while lorazepam was associated with slower sedation. Rescue medication was reported in 16% of droperidol cases, 20% of olanzapine cases, 13% of midazolam cases, and 46% of lo
- Routine Gastric Residual Checks In Critically Ill Childrenhttps://reachmd.com/news/gastric-residual-checks-critically-ill-children/2487476/Key Takeaways No routine assessment was noninferior for survival and days free of mechanical ventilation at 30 days in the randomized comparison. Early nutrition delivery was modestly higher, and time with no enteral feed was shorter, in the group with
- Obexelimab Lowers Flare Risk in IgG4-Related Diseasehttps://reachmd.com/news/obexelimab-lowers-flare-risk-in-igg4-related-disease/2487459/Key Takeaways Weekly obexelimab was associated with a longer time to first flare requiring rescue therapy and a lower observed flare risk than placebo. By week 52, complete remission was more common and cumulative rescue glucocorticoid use was lower wi