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Partial Response in Major Depressive Disorder Treatment: Are We Doing Enough?



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Addressing unresolved symptoms in patients with major depressive disorder using the latest guidelines, tools, and treatment options.

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  • Overview

    Although traditional antidepressants are often used for the first-line treatment of major depressive disorder, it’s common to see only a partial response in patients, which is defined as a 25 to 50 percent reduction in depressive symptoms.1 Fortunately, there are tools and therapeutic approaches we can use to identify and treat unresolved symptoms, such as validated scales and various pharmacologic strategies, including augmentation. Joining Dr. Charles Turck to discuss how we can address this unmet need in major depressive disorder care are Drs. Rakesh Jain and Clay Jackson. Dr. Jain is a Clinical Professor in the Department of Psychiatry at Texas Tech University School of Medicine in Permian Basin, and Dr. Jackson is a Clinical Assistant Professor of Family Medicine and Psychiatry at the University of Tennessee College of Medicine in Memphis.


    1. Fava M. Diagnosis and definition of treatment-resistant depression. Biol Psychiatry. 2003;53(8):649-659. doi:10.1016/s0006-3223(03)00231-2.  

    January 2024 US.UNB.X.23.00145

Schedule23 Apr 2024