There is a dramatically uneven distribution of risk among women for colorectal cancer, the second most common cancer in America. Low-risk women have only five percent lifetime odds of developing the disease, while moderate and high-risk subsets are much more vulnerable. What accounts for this risk? The evidence points to a series of genetic and environmental factors, along with other known syndromes. Dr. Steven Stryker, professor of clinical oncology at Northwestern University’s Feinberg School of Medicine, joins host Dr. Lauren Streicher to evaluate common predispositions to this devastating disease.