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Dr. Jeffrey Settleman is a professor of medicine at Harvard Medical School and the Laurel Schwartz Professor of Oncology. He is director of the Center for Molecular Therapeutics at the Massachusetts General Hospital Cancer Center and scientific director of the Cancer Center Massachusetts General Hospital. Dr. Settleman is an international leader in the study of cellular signaling pathways mediated by GTPases and kinases in human cancer. His current research is largely focused on molecularly-targeted cancer therapeutics, personalized cancer medicine, and mechanisms of drug resistance.

Dr. Settleman received a PhD in genetics from Yale University in 1989 and was a postdoctoral fellow at the Whitehead Institute for Biomedical Research at MIT in the laboratory of Dr. Robert Weinberg from 1989-1992. Dr. Settleman joined the faculty at Harvard Medicine School in 1992.

Dr. Settleman is the recipient of the Faculty Research Award from the American Cancer Society, and he has received several awards from private foundations, including the Avon Foundation, the Bertucci Foundation, the Saltonstall Foundation, the V Foundation, and the Samuel Waxman Cancer Research Foundation. He has authored more than 120 scientific publications and serves on the editorial boards of Developmental Cell, Molecular Biology of the Cell, and Molecular and Cellular Biology.