Study Links Skin Microbiota and AD Alleviation via Melatonin
Key Takeaways
- Melatonin alters the skin microbiota in AD mice, increasing microbiota-derived SCFAs, particularly propionic acid.
- Propionic acid suppresses FABP5 expression through GPR43, reducing AD symptoms in both mice and HaCaT cells.
- Targeting the skin microbiota using melatonin or SCFA-related...
A new study published in the Journal of Allergy and Clinical Immunology indicates melatonin has been shown to reduce atopic dermatitis (AD) symptoms by altering skin microbiota composition, with short...
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