Clinical Trial Marks New Chapter for Gene Therapy
https://reachmd.com/news/clinical-trial-marks-new-chapter-for-gene-therapy/2457472/
First to use “spreading vector” technique In the quest to cure inherited retinal diseases, Casey Eye Institute is using a novel gene therapy viral vector and surgical approach. The setting? A clinical trial for treatment of X-linked juvenile retinoschisis…
Schisanhenol Suppresses Cytokine Storm and Acute Lung Injury in Mice
https://reachmd.com/news/schisanhenol-suppresses-cytokine-storm-and-acute-lung-injury-in-mice/2457483/
Background and objectives Cytokine storm (CS) is an acute systemic inflammatory response with limited effective interventions up to now. The treatment experience of the COVID-19 pandemic suggests great potential in the intervention of CS by herbal medicine. This study aimed to inve…
Novel Treatment for Polycythemia Vera Shows Promise in Clinical Trial
https://reachmd.com/news/novel-treatment-for-polycythemia-vera-shows-promise-in-clinical-trial/2457480/
A novel treatment for polycythemia vera, a potentially fatal blood cancer, demonstrated the ability to control overproduction of red blood cells, the hallmark of this malignancy and many of its debilitating symptoms in a multi-center clinical trial led by the Icahn School of Medicin…
How Fusion Proteins Hijack Gene Regulators to Spur Childhood Cancer
https://reachmd.com/news/how-fusion-proteins-hijack-gene-regulators-to-spur-childhood-cancer/2457473/
BUFFALO, N.Y., — Many childhood cancers start with a hijacking at the molecular level. A group of abnormal proteins known as fusion proteins aberrantly engage with a collection of proteins that switches genes on and off. As a result, genes that should be activated get repressed and genes that shoul…
Children Surpass a Year of HIV Remission After Treatment Pause
https://reachmd.com/news/children-surpass-a-year-of-hiv-remission-after-treatment-pause/2457459/
Four children have remained free of detectable HIV for more than one year after their antiretroviral therapy (ART) was paused to see if they could achieve HIV remission, according to a presentation today at the 2024 Conference on Retroviruses and Opportunistic Infections (CROI) in Denver. The chi…
Doctors Found Tiny Microplastics in People’s Arteries. Their Presence Was Tied to a Higher Risk of Heart Disease
https://reachmd.com/news/doctors-found-tiny-microplastics-in-peoples-arteries-their-presence-was-tied-to-a-higher-risk-of-heart-disease/2457466/
People with microplastics and nanoplastics in plaque lining a major blood vessel in their neck may have a higher risk of heart attack, stroke or death, new research suggests. The findings, published Wednesday in The New England Journal of Medicine, are the first time scientists have linked these ti…
25 Million US Dollars for International Cancer Research
https://reachmd.com/news/25-million-us-dollars-for-international-cancer-research/2457449/
image: Ma…
Earliest-Yet Alzheimer’s Biomarker Found in Mouse Model Could Point to New Targets
https://reachmd.com/news/earliest-yet-alzheimers-biomarker-found-in-mouse-model-could-point-to-new-targets/2457456/
CHAMPAIGN, Ill. — A surge of a neural-specific protein in the brain is the earliest-yet biomarker for Alzheimer’s disease, report University of Illinois Urbana-Champaign researchers studying a mouse model of the disease. Furthermore, the increased protein activity leads to the seizures associated…
Low Iron Levels Resulting from Infection Could Be Key Trigger of Long COVID
https://reachmd.com/news/low-iron-levels-resulting-from-infection-could-be-key-trigger-of-long-covid/2457438/
The discovery not only points to possible ways to prevent or treat the condition, but could help explain why symptoms similar to those of long COVID are also commonly seen in a number of post-viral conditions and chronic inflammation. Although estimates are highly variable, as many as three in 10 …
Study Shows New Class of Antivirals That Works Against SARS-CoV-2
https://reachmd.com/news/study-shows-new-class-of-antivirals-that-works-against-sars-cov-2/2457436/
EDMONTON — A University of Alberta research team has uncovered a new class of drugs with the potential to prevent or treat infections in a future viral outbreak. In the paper, published this week in Nature, the team reports that SARS-CoV-2 — the virus that causes CO…