Showing 8801-8810 of 18571 results for "".
- Povorcitinib Improves Lesion Burden and Pain in Hidradenitis Suppurativahttps://reachmd.com/news/povorcitinib-improves-lesion-burden-and-pain-in-hidradenitis-suppurativa/2485551/Oral povorcitinib produced early and sustained improvements in lesion burden and pain in patients with moderate-to-severe hidradenitis suppurativa (HS), according to “Effect of Povorcitinib on Hidradenitis Suppurativa Lesions Through 24 Weeks in STOP-HS Trials,” a poster by Jennifer L. Hsiao, MD,
- ORKA-001 Phase 1 Data Support Potential Once-Yearly IL-23 Dosinghttps://reachmd.com/news/orka-001-phase-1-data-support-potential-once-yearly-il-23-dosing/2485550/A half-life–extended IL-23p19 monoclonal antibody demonstrated sustained pharmacokinetics and favorable tolerability that may support once-yearly dosing in plaque psoriasis, according to “Phase 1 Clinical Data of ORKA-001, a Novel Half-Life–Extended IL-23p19 Monoclonal Antibody,” a poster by Jame
- Dupilumab Produces Early and Sustained Improvements in CSU Activityhttps://reachmd.com/news/dupilumab-produces-early-and-sustained-improvements-in-csu-activity/2485548/Dupilumab produced early and sustained reductions in urticaria activity in patients with chronic spontaneous urticaria (CSU), according to “Dupilumab Provides Early and Sustained Improvement in Urticaria Activity in Patients With Chronic Spontaneous Urticaria,” a poster by Jonathan A. Bernstein,
- Mechanistic Insights into TP53 Inactivation and SCD1 Upregulation Driving Brain Metastasis in Breast Cancerhttps://reachmd.com/news/mechanistic-insights-into-tp53-inactivation-and-scd1-upregulation-driving-brain-metastasis-in-breast-cancer/2485448/TP53 loss and SCD1 upregulation are pervasive features of breast cancer brain metastasis and are linked to aggressive disease biology; TP53 inactivation is specifically associated with this clinical phenotype. In vivo, TP53 perturbation increased the capacity of tumor cells to colon
- Advancements in Lab-Grown Corticospinal Neurons for ALS and Spinal Injury Researchhttps://reachmd.com/news/advancements-in-lab-grown-corticospinal-neurons-for-als-and-spinal-injury-research/2485521/New evidence demonstrates that corticospinal-like neurons can be generated in vitro with high subtype specificity and fidelity, providing a developmentally informed mod
- Molecular Evolution of SARS-CoV-2 in Immunocompromised Patients: Clinical Insights and Management Strategieshttps://reachmd.com/news/molecular-evolution-of-sars-cov-2-in-immunocompromised-patients-clinical-insights-and-management-strategies/2485522/Replication‑competent SARS‑CoV‑2 persisted for months to years in three immunocompromised patients, driving intra‑host viral evolution and prompting reconsideration of surveillance and treatment strategies. The team performed detailed longitudinal virologic assessmen
- Revolutionizing Cancer Therapy: The Impact of Macrophage-Targeting Immunotherapyhttps://reachmd.com/news/revolutionizing-cancer-therapy-the-impact-of-macrophage-targeting-immunotherapy/2485523/Mount Sinai researchers developed a macrophage-targeting immunotherapy —
- Electrical Impedance Tomography in Pediatric Extubation: New Findings and Implicationshttps://reachmd.com/news/electrical-impedance-tomography-in-pediatric-extubation-new-findings-and-implications/2485527/Electrical impedance tomography (EIT) detects real-time peri-extubation changes in lung physiology in critically ill children and provides detailed physiologic characterization of the immediate post-extubation period. This physiologic signal was captured in
- Rethinking Support for Breastfeeding: Addressing Trauma to Improve Outcomeshttps://reachmd.com/news/rethinking-support-for-breastfeeding-addressing-trauma-to-improve-outcomes/2485528/A recent narrative review finds that prior psychological trauma is associated with lower breastfeeding initiation and shorter duration, and emphasizes the importance of p
- Telesurgery vs. Robotic Surgery: Innovations in Urologic Oncologyhttps://reachmd.com/news/telesurgery-vs-robotic-surgery-innovations-in-urologic-oncology/2485531/A randomized, multicenter non-inferiority trial found remote telesurgery to be non-inferior to local robotic surgery for radical prostatectomy and partial nephrec