Showing 4861-4870 of 20470 results for "".
- Metformin and Exercise-Linked Metabolite Lac‑Phe in Prostate Cancer Patientshttps://reachmd.com/news/metformin-exercise-metabolite-lac-phe-prostate-cancer/2486528/Metformin treatment was observed to increase circulating N-lactoyl-phenylalanine (Lac-Phe) in men with prostate cancer, with blood levels similar to those reported after stre
- Western Diet Linked to Faster FDG‑PET Metabolic Decline in Older Womenhttps://reachmd.com/news/western-diet-faster-fdgpet-decline-older-women/2486522/Key Takeaways: In an overall cohort analysis, investigators reported no statistically significant associations between baseline Western or Prudent dietary pattern scores and longitudinal FDG-PET SUVR. After sex stratification, higher baseline Western d
- CLL Linked to Higher Skin Cancer Risk and Worse Outcomes in Nationwide Studyhttps://reachmd.com/news/cll-linked-to-higher-skin-cancer-risk-and-worse-outcomes-in-nationwide-study/2486526/Patients with chronic lymphocytic leukemia (CLL) face a significantly elevated risk of developing skin cancer, according to a nationwide Danish cohort study spanning three decades. Study investigators analyzed registry data fr
- Phase 3 Data Highlight Early and Broad Response With Deuruxolitinibhttps://reachmd.com/news/phase-3-data-highlight-early-and-broad-response-with-deuruxolitinib/2486483/Two posters presented at the American Academy of Dermatology (AAD) 2026 Annual Meeting provide complementary Phase 3 evidence supporting the efficacy of deuruxolitinib, an oral Janus kinase (JAK)1/JAK2 inhibitor, in adults with severe alopecia areata (AA). Both analyses pooled data from th
- KT Taping Shows Small, Uncertain Benefits in Reviewhttps://reachmd.com/news/kt-taping-shows-small-uncertain-benefits-in-review/2486511/Key Takeaways: This overview of systematic reviews found small, short-term improvements in pain and function with KT taping, supported by low to very low certainty evidence. Effects beyond the immediate term were generally negligible or inconclusive ac
- Gene-Edited Therapy Shows Early Promise in Sickle Cellhttps://reachmd.com/news/gene-edited-therapy-shows-early-promise-in-sickle-cell/2486510/Key Takeaways: In a small NEJM-reported trial (n=28), most patients were free of vaso-occlusive crises during follow-up after a single gene-edited cell therapy. Hemoglobin levels increased and fetal hemoglobin was elevated at 6 months, with reported pe
- Acylcarnitines Linked to MetS and Hypertension in Cohortshttps://reachmd.com/news/acylcarnitines-linked-to-mets-and-hypertension-in-cohorts/2486516/Key Takeaways: Acylcarnitine profiles were associated with MetS features and blood pressure in women with obesity across two cohorts. MC and LC acylcarnitines, including specific species, were associated with hypertension, with LC acylcarnitines indepe
- Assessing RV Adaptation Requires Multiparametric Approachhttps://reachmd.com/news/assessing-rv-adaptation-requires-multiparametric-approach/2486517/Key Takeaways: RV adaptation to pressure overload is described as a continuum in which single metrics are insufficient across changing loading conditions. Load-informed and coupling-oriented indices (e.g., TAPSE/SPAP, LAIRV) are proposed as complementa
- Brain–Blood Signals in MDD Show Limited Concordancehttps://reachmd.com/news/brainblood-signals-in-mdd-show-limited-concordance/2486509/Key Takeaways: A review reports evidence of partial concordance between brain and blood multiomic signals in MDD, with limited overlap with GWAS-identified risk loci. Individual gene-level findings are highly variable, but recurring pathway-level theme
- FDA Clarifies GLP-1 Compounding as Shortages Evolvehttps://reachmd.com/news/fda-clarifies-glp-1-compounding-as-shortages-evolve/2486512/Key Takeaways: FDA reiterates that 503A compounding must be patient-specific and is restricted when products are “essentially copies” of commercially available drugs. The agency describes its interpretation of “essentially a copy,” including an illustr