Showing 4671-4680 of 20465 results for "".
- Tirzepatide Maintained Weight Loss In SURMOUNT-MAINTAINhttps://reachmd.com/news/tirzepatide-maintained-weight-loss-in-surmount-maintain/2487192/Key Takeaways Continued tirzepatide at the maximum tolerated dose was associated with greater maintenance of bodyweight reduction than switching to placebo at week 112. The 5 mg group showed an intermediate result, and rescue therapy after substantial
- Molecular Profiling Guides Adjuvant Therapy in Endometrial Cancerhttps://reachmd.com/news/molecular-profiling-guides-adjuvant-therapy-in-endometrial-cancer/2487196/Key Takeaways Non-inferiority for vaginal recurrence was reported, although recurrence was numerically higher with molecular-profile guided treatment. Favorable profiles were assigned to observation, intermediate profiles to brachytherapy, and unfavora
- FDA Clears Caliway’s Phase 3 CBL-514 Trial for Abdominal Fat Reductionhttps://reachmd.com/news/fda-clears-caliways-phase-3-cbl-514-trial-for-abdominal-fat-reduction/2487183/Caliway Biopharmaceuticals announced that the US Food and Drug Administration (FDA) cleared the Investigational New Drug application for CBL-0302, also known as SUPREME-02, its second global pivotal phase 3 study of CBL-514 for abdominal subcutaneous fat reduction.1 The IND pass
- Cerebral Oxygenation-Guided Resuscitation and MRI Outcomes In Preterm Neonateshttps://reachmd.com/news/cosgod-mri-preterm-neonates/2487174/Key Takeaways In preterm infants, MRI-defined brain injury incidence did not differ between NIRS-guided and control groups. The NIRS group showed a larger biparietal diameter, with a reported trend toward fewer abnormal biparietal diameter findings.
- UC Trial Tests Non-Opioid Relief For Severe Post-Stroke Headacheshttps://reachmd.com/news/uc-trial-tests-non-opioid-relief-for-severe-post-stroke-headaches/2487180/Key Takeaways BLOCK-SAH is enrolling patients recovering from SAH to compare ropivacaine plus dexamethasone injection with saline placebo. The primary objective is opioid use within 24 hours, with additional assessment of pain intensity, tolerability,
- Evaluating an Antibiotic Stewardship for Sore Throat in Primary Carehttps://reachmd.com/news/stewardship-sore-throat-primary-care/2487175/Key Takeaways A 6-month antimicrobial stewardship program for acute sore throat combined guideline-reflection meetings, didactic case discussions, local quality improvement work, and repeated audit and feedback using laboratory and prescribing data. Lo
- Long-Term HBV DNA Response Patterns Track Outcomes In Cirrhosishttps://reachmd.com/news/hbv-dna-patterns-cirrhosis/2487176/Key Takeaways HBV DNA response patterns during the first two years of nucleos(t)ide analog therapy identified distinct long-term outcome groups in patients with HBV-related cirrhosis. Patients with maintained virological response had lower hepatocellul
- Host-Response Optimization Trial After Ultra-Low Anterior Resectionhttps://reachmd.com/news/host-response-optimization-trial-after-ultra-low-anterior-resection/2487160/Key Takeaways Twenty-four-month disease-free survival and overall survival were both higher in the intervention group than in the standard ERAS group. Functional recovery was better with the integrated program across bowel, sleep, psychological, and se
- Esketamine-Led Opioid-Free Anaesthesia Lowers PPCs in Bariatric Surgeryhttps://reachmd.com/news/esketamine-led-opioid-free-anaesthesia-lowers-ppcs-in-bariatric-surgery/2487151/Key Takeaways Esketamine-led opioid-free anesthesia was associated with lower postoperative pulmonary complication rates and lower hypoxemia incidence in this randomized bariatric surgery trial. Twenty-four-hour opioid consumption was lower while posto
- External Validation of Deep Learning for Dysplastic Barrett's Esophagushttps://reachmd.com/news/external-validation-of-deep-learning-for-dysplastic-barretts-esophagus/2487156/Key Takeaways External validation of a previously cross-validated Barrett's esophagus dysplasia model used 489 whole-slide images from three academic centers. Sensitivity and specificity varied across nondysplastic Barrett's esophagus, low-grade dyspla