Showing 3611-3620 of 20433 results for "".
- COLOR III Short-Term Outcomes for TaTME Versus LapTMEhttps://reachmd.com/news/color-iii-short-term-outcomes-for-tatme-versus-laptme/2487893/Key Takeaways TaTME was associated with a lower need for conversion than LapTME in this randomized comparison. Ninety-day morbidity and anastomotic leakage were reported at similar levels across the two surgical groups. Specimen quality and ma
- CagriSema Add-On to Basal Insulin Meets Phase 3 Endpointshttps://reachmd.com/news/cagrisema-add-on-to-basal-insulin-meets-phase-3-endpoints/2487895/Key Takeaways Both weekly cagrilintide-semaglutide dose levels met the primary endpoint and were associated with greater HbA1c lowering than placebo by week 40. Bodyweight reductions of 10% to 12% were reported across the active-dose groups. A
- Mezigdomide Triplet Improves PFS in SUCCESSOR-2 Myeloma Trialhttps://reachmd.com/news/mezigdomide-triplet-improves-pfs-in-successor-2-myeloma-trial/2487873/Key Takeaways The triplet was associated with longer progression-free survival, with a hazard ratio of 0.48. The comparison came from an open-label, randomized phase 3 trial in previously treated myeloma after anti-CD38 antibody and lenalidomide exposu
- AI Clinical Support Tool Improved Primary Care Decisionshttps://reachmd.com/news/ai-clinical-support-tool-improved-primary-care-decisions/2487871/Key Takeaways AI support was associated with better documentation and treatment planning, while short-term treatment failure did not differ significantly from standard care. Hospitalisation, death, and patient satisfaction were similar between groups,
- CUORE and SCORE2 Validation in an Italian Primary Care Cohorthttps://reachmd.com/news/cuore-and-score2-validation-in-an-italian-primary-care-cohort/2487853/Key Takeaways Both models showed moderate 10-year discrimination, with CUORE showing slightly higher AUC ranges than SCORE2. Broader administrative endpoint ascertainment was associated with higher observed event rates for both models without materiall
- MRI Radiomics Score And ADC Improve HCC Recurrence Predictionhttps://reachmd.com/news/mri-radiomics-score-and-adc-improve-hcc-recurrence-prediction/2487851/Key Takeaways Lower ADC values and higher radiomics scores were associated with early recurrence, and their combination showed better discrimination than either metric alone. Larger tumor size, multiple lesions, lower ADC values, and higher radiomics s
- ARCHER Trial Explores Vaccine Strategy to Prevent ALK Inhibitor Resistance in Advanced NSCLChttps://reachmd.com/news/archer-trial-explores-vaccine-strategy-to-prevent-alk-inhibitor-resistance-in-advanced-nsclc/2487574/Targeted therapies have transformed outcomes for patients with ALK-positive non-small cell lung cancer (NSCLC), but acquired resistance remains a persistent obstacle. Acquired resistance is often mediated by mutations within the ALK kinase domain, limiting the durability of tyrosine kinase
- SPH3127 Phase III Trial Reports Noninferior Blood Pressure Loweringhttps://reachmd.com/news/sph3127-phase-iii-trial-reports-noninferior-blood-pressure-lowering/2487781/Key Takeaways SPH3127 100 mg once daily was associated with week 12 blood pressure lowering that was noninferior to valsartan on the prespecified primary endpoint. Stage 1 supported carrying forward the 100 mg dose after it showed the largest week 12 m
- Laser Speckle Imaging Shows Promise for Objective Rosacea Assessment: Analysishttps://reachmd.com/news/laser-speckle-imaging-shows-promise-for-objective-rosacea-assessment-analysis/2487680/
- Stopping Beta Blockers After Myocardial Infarctionhttps://reachmd.com/news/stopping-beta-blockers-after-myocardial-infarction/2487597/Key Takeaways Discontinuation was noninferior to continuation for the composite outcome studied. Stable post-MI patients with a left ventricular ejection fraction of at least 40% and no heart failure were randomized after at least 1 year of therapy to