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PTSD Unmet Needs: A Lens on Burden, Impact, and Treatment Challenges



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Tune in for a discussion on disease burden, unmet needs, and clinical challenges in PTSD.

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  • Overview

    Post-traumatic stress disorder (PTSD) is associated with a high impact on the individual and can impair interpersonal, occupational, and social functions.1 Underdiagnosis and undertreatment of PTSD may lead to potential adverse outcomes, such as overall quality of life, suicide attempts, and increased risk of mortality.2-6 To learn more, dive in with Dr. Charles Turck as he speaks with Dr. John Krystal, Chair of Psychiatry at Yale School of Medicine. 


    1. Rodriguez P, Holowka DW, Marx BP. Assessment of posttraumatic stress disorder-related functional impairment: a review. J Rehabil Res Dev. 2012;49(5):649. doi:10.1682/JRRD.2011.09.0162
    2. Priebe S, Matanov A, Janković Gavrilović J, et al. Consequences of untreated posttraumatic stress disorder following war in former Yugoslavia: morbidity, subjective quality of life, and care costs. Croat Med J. 2009;50(5):465-475. doi:10.3325/cmj.2009.50.465
    3. Gagnon-Sanschagrin P, Schein J, Urganus A, et al. Identifying individuals with undiagnosed post-traumatic stress disorder in a large United States civilian population – a machine learning approach. BMC Psychiatry. 2022;22(1):630. doi:10.1186/s12888-022-04267-6
    4. Wimalawansa S. Post-traumatic stress disorder: an under-diagnosed and under-treated entity. Compr Res J Med Med Sci . 2013;1:1-12.
    5. Goenjian AK, Walling D, Steinberg AM, Karayan I, Najarian LM, Pynoos R. A prospective study of posttraumatic stress and depressive reactions among treated and untreated adolescents 5 years after a catastrophic disaster. Am J Psychiatry. 2005;162(12):2302-2308. doi:10.1176/appi.ajp.162.12.2302
    6. Cooper J, Metcalf O, Phelps A. PTSD--an update for general practitioners. Aust Fam Physician. 2014;43(11):754-757.

    January 2024 US.UNB.X.23.00120

Schedule24 Apr 2024