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Inflammatory Pathways in Severe Asthma: Focus on Mucus Plugs

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Explore the role and underlying clinical outcome pathology of mucus plugging in severe asthma.

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  • Overview

    It’s only been a recent discovery that mucus plugging may be present and persistent in chronic severe asthma.1 In fact, studies have shown that mucus plugs may drive some lung function deficits in severe asthma.1 Given this recent finding, Dr Charles Turck speaks with Professor Arnaud Bourdin about the clinical significance and pathogenesis of mucus plugging in severe asthma. Professor Bourdin is Head of Pulmonology at Arnaud de Villeneuve Hospital in Montpellier, France.

    Reference:

    1. Dunican EM, Watchorn DC, Fahy JV. Ann Am Thorac Soc. 2018;15(Suppl 3):S184-S191. doi:10.1513/AnnalsATS.201807-485AW

    ©2024 Amgen and AstraZeneca. All rights reserved. US-86740 Last Updated 3/24 

Schedule23 Apr 2024