Primary and secondary amenorrhea can have various underlying causes among adolescents, including polycystic ovarian syndrome (or PCOS), thyroid disease, and atypical body weight. What types of behavior and lifestyle modifications should be the first steps for adolescent patients with irregular menstruation? Dr. Suleena Kalra, assistant professor in the department of obstetrics and gynecology at Penn Medicine, discusses ways to regulate periods among adolescent patients and protect their future fertility. How significant a role might stress play in amenorrhea among these patients? Dr. Lee Freedman hosts.