What are the components of useful, evidence-based data? Dr. Robert Wild discusses with host Dr. Alan Brown the spectrum of data — from expert opinion, to observational studies, to different types of analytic studies, including cross-sectional, case-controlled studies, cohort studies, and clinical trials — and the shortcomings and biases of each. Dr. Wild explores cardiovascular epidemiology, clinical interpretation of biostatistical principles and how to critically evaluate research, in order to better integrate evidence, experience and patient values in clinical decisions.