Who would expect that a hole in the heart and a pain in the head are related? If you take care of patients who suffer from migraine headaches, host Dr. Janet Wright's interview with Dr. Jill Jesurum, scientific director of the Heart & Vascular Institute at Swedish Medical Center in Seattle, may shed light on some unanticipated benefits of treatment for migraineurs. Dr. Jesurum explains how patent foramen ovale (PFO) closure may impact the symptoms experienced by a migraine sufferer, and shares her perspective on which populations may benefit most from a PFO procedure.