Childhood obesity is a significant health concern in the US and worldwide. How does obesity impact a child's cardiovascular function and influence future risk of heart disease? Dr. Nathalie Farpour-Lambert, head of the Pediatric Exercise Medicine and Obesity Care Program in the department of pediatrics at the University Hospitals of Geneva in Switzerland, discusses new findings about the effect of a modest amount of physical activity in improving blood pressure, arterial function and arterial wall thickness in obese children. How can clinicians overcome the biggest challenges in encouraging a healthy lifestyle for their pediatric patients?