Although HIV transmission through breast milk is a significant global health issue, many mothers and their babies depend on breastfeeding for survival. About 90% of children who become infected with HIV each year are in sub-Saharan Africa. What therapeutic interventions are recommended for mothers with HIV in order to prevent transmission of the virus to their babies? Dr. Lynne Mofenson, chief of the pediatric, adolescent and maternal AIDS branch at the National Institute of Child Health and Human Development, at the National Institutes of Health in Rockville, Maryland, discusses two exciting new developments found to reduce the risk of HIV transmission from mothers to their babies in places where replacement feeding for infants isn't available. Hosted by Dr. Maurice Pickard.