Insulin resistance in muscle, liver and ß-cell represent the core pathophysiologic defects in type 2 diabetes. In addition, the ominous octet all play important roles in the development of glucose intolerance in people with type 2 diabetes. How will this new paradigm shift our understanding in the way we treat our type 2 patients? Dr. Ralph DeFronzo, professor of medicine and author of the recent Banting Lecture, “From the Triumvirate to the Ominous Octet: A New Paradigm for the Treatment of Type 2 Diabetes Mellitus,” discusses new therapies based on the pathophysiology. Join host Dr. Steven Edelman to learn more.
