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Making the Case for Dual Ang-2/VEGF-A Inhibition: Anatomical Benefits 

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15 minutes
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  • Overview

    What evidence do we have that blocking Ang-2 and VEGF-A is beneficial for patients? Tune in to hear Dr. Jennifer Lim and Dr. Carl Regillo examine the anatomical and biomarker evidence surrounding dual inhibition of Ang-2 and VEGF-A. Find out how bispecific targeting can benefit patients with neovascular age-related macular degeneration and diabetic macular edema.   

  • Disclosure of Relevant Financial Relationships

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Host:
    Jennifer I. Lim, MD, FARVO 
    Marion H Schenk Chair
    UIC Distinguished Professor of Ophthalmology
    Vice Chair, Director of Retina Services
    University of Illinois at Chicago
    Chicago, IL

    Dr. Lim has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:
    Research: Adverum, Aldeyra, Chengdu Kanghong, Genentech, Graybug, Janssen, NGM, Ocular Therapeutix, Regeneron, REGENXBIO, Spring Vision, Stealth BioTherapeutics
    Consulting Fees: AbbVie/Allergan, Alimera, Aura, Bausch + Lomb, Cognition, Eyenuk, EyePoint, Genentech/Roche, Iveric, LuxaBio, Regeneron, Unity, Viridian

    Faculty:
    Carl D. Regillo, MD
    Director, Retina Service
    Wills Eye Hospital
    Philadelphia, PA

    Dr. Regillo has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:
    Research: 4DMT, Adverum, Allergan, Annexon, Apellis, Astellas, EyePoint, Genentech, Gyroscope, lveric, Janssen, Kodiak, Lineage, NGM, Notal, Novartis, Ocugen, Opthea, Regeneron, REGENXBIO
    Consulting Fees: 4DMT, Adverum, Alcon, Allergan, Annexon, Apellis, Aviceda, Clearside, Cognition, EyePoint, Genentech, lveric, Janssen, Kodiak, Lineage, Merck, NGM, Novartis, Ocugen, Ocuphire, OcuTerra, Ray, Regeneron, REGENXBIO, Stealth, Thea, Zeiss

    Reviewers/Content Planners/Authors:

    • Stephen Chavez has nothing to disclose.
    • Cindy Davidson has nothing to disclose.
    • Ann Early has nothing to disclose.
    • Brian P. McDonough, MD, FAAFP, has nothing to disclose
    • Tim Person has nothing to disclose.
    • Mara Siegel has nothing to disclose.
    • Stephanie Wenick has provided medical writing services to REGENXBIO Inc.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Explore emerging evidence of the benefits of dual Ang-2/VEGF suppression on anatomical outcomes of patients with neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME)
    • Identify patients with DME or nAMD who would benefit from treatment with suppression of VEGF and Ang-2
  • Target Audience

    This activity is designed to meet the educational needs of retina specialists, ophthalmologists, and other eye health professionals.  

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. 

    Global Learning Collaborative (GLC) designates this enduring activity for a maximum of .25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for .25 nursing contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for .25 AAPA Category 1 CME credits. Approval is valid until April 30, 2025. PAs should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    Prova Education designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties.  

    Prova Education's methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the best education in the most impactful manner and to verify its results with progressive outcomes research. 

  • Commercial Support

    This activity is supported by an independent educational grant from Genentech, a member of the Roche Group.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to access a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site. 

    Reproduction Prohibited 
    Reproduction of this material is not permitted without written permission from the copyright owner. 

  • System Requirements

    • Supported Browsers (2 most recent versions):
      • Google Chrome for Windows, Mac OS, iOS, and Android
      • Apple Safari for Mac OS and iOS
      • Mozilla Firefox for Windows, Mac OS, iOS, and Android
      • Microsoft Edge for Windows
    • Recommended Internet Speed: 5Mbps+

  • Publication Dates

    Release Date:

    Expiration Date:

Recommended
Details
Presenters
Related
Comments
  • Overview

    What evidence do we have that blocking Ang-2 and VEGF-A is beneficial for patients? Tune in to hear Dr. Jennifer Lim and Dr. Carl Regillo examine the anatomical and biomarker evidence surrounding dual inhibition of Ang-2 and VEGF-A. Find out how bispecific targeting can benefit patients with neovascular age-related macular degeneration and diabetic macular edema.   

  • Disclosure of Relevant Financial Relationships

    In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Host:
    Jennifer I. Lim, MD, FARVO 
    Marion H Schenk Chair
    UIC Distinguished Professor of Ophthalmology
    Vice Chair, Director of Retina Services
    University of Illinois at Chicago
    Chicago, IL

    Dr. Lim has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:
    Research: Adverum, Aldeyra, Chengdu Kanghong, Genentech, Graybug, Janssen, NGM, Ocular Therapeutix, Regeneron, REGENXBIO, Spring Vision, Stealth BioTherapeutics
    Consulting Fees: AbbVie/Allergan, Alimera, Aura, Bausch + Lomb, Cognition, Eyenuk, EyePoint, Genentech/Roche, Iveric, LuxaBio, Regeneron, Unity, Viridian

    Faculty:
    Carl D. Regillo, MD
    Director, Retina Service
    Wills Eye Hospital
    Philadelphia, PA

    Dr. Regillo has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:
    Research: 4DMT, Adverum, Allergan, Annexon, Apellis, Astellas, EyePoint, Genentech, Gyroscope, lveric, Janssen, Kodiak, Lineage, NGM, Notal, Novartis, Ocugen, Opthea, Regeneron, REGENXBIO
    Consulting Fees: 4DMT, Adverum, Alcon, Allergan, Annexon, Apellis, Aviceda, Clearside, Cognition, EyePoint, Genentech, lveric, Janssen, Kodiak, Lineage, Merck, NGM, Novartis, Ocugen, Ocuphire, OcuTerra, Ray, Regeneron, REGENXBIO, Stealth, Thea, Zeiss

    Reviewers/Content Planners/Authors:

    • Stephen Chavez has nothing to disclose.
    • Cindy Davidson has nothing to disclose.
    • Ann Early has nothing to disclose.
    • Brian P. McDonough, MD, FAAFP, has nothing to disclose
    • Tim Person has nothing to disclose.
    • Mara Siegel has nothing to disclose.
    • Stephanie Wenick has provided medical writing services to REGENXBIO Inc.
  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Explore emerging evidence of the benefits of dual Ang-2/VEGF suppression on anatomical outcomes of patients with neovascular age-related macular degeneration (nAMD) and diabetic macular edema (DME)
    • Identify patients with DME or nAMD who would benefit from treatment with suppression of VEGF and Ang-2
  • Target Audience

    This activity is designed to meet the educational needs of retina specialists, ophthalmologists, and other eye health professionals.  

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team. 

    Global Learning Collaborative (GLC) designates this enduring activity for a maximum of .25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) designates this activity for .25 nursing contact hours. Nurses should claim only the credit commensurate with the extent of their participation in the activity.

    Global Learning Collaborative (GLC) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit for activities planned in accordance with AAPA CME Criteria. This activity is designated for .25 AAPA Category 1 CME credits. Approval is valid until April 30, 2025. PAs should claim only the credit commensurate with the extent of their participation in the activity.

  • Provider(s)/Educational Partner(s)

    Prova Education designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties.  

    Prova Education's methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the best education in the most impactful manner and to verify its results with progressive outcomes research. 

  • Commercial Support

    This activity is supported by an independent educational grant from Genentech, a member of the Roche Group.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to access a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site. 

    Reproduction Prohibited 
    Reproduction of this material is not permitted without written permission from the copyright owner. 

  • System Requirements

    • Supported Browsers (2 most recent versions):
      • Google Chrome for Windows, Mac OS, iOS, and Android
      • Apple Safari for Mac OS and iOS
      • Mozilla Firefox for Windows, Mac OS, iOS, and Android
      • Microsoft Edge for Windows
    • Recommended Internet Speed: 5Mbps+

  • Publication Dates

    Release Date:

    Expiration Date:

Schedule12 Nov 2024