Innovations in Oncology Learning: Hematologic Malignancies

Overview
This enduring activity, presented in collaboration with the National Comprehensive Cancer Network (NCCN®), focuses on translating oncology clinical practice guidelines into practical strategies for treating CLL/SLL and MCL. Participants will learn how to integrate clinical trial data into guideline-concordant treatment plans for patients that have progressed following a covalent BTK inhibitor. The program highlights the importance of evidence-based approaches and the use of noncovalent BTK inhibitors for relapsed/refractory CLL/SLL and MCL. Attendees will also explore emerging data that could influence future treatment guidelines, and a case example of a patient with CLL/SLL relapsing after 2 prior lines of therapy, including a BTK inhibitor and a BCL-2 inhibitor.
Disclosure of Relevant Financial Relationships
In accordance with the ACCME Standards for Integrity and Independence, Global Learning Collaborative (GLC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any ineligible company. GLC mitigates all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.
Faculty:
Seema Ali Bhat, MD
Associate Professor, Division of Hematology
Department of Internal Medicine
The Ohio State University
Columbus, OH
Dr. Bhat has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:
Research support: AstraZeneca
Consulting fees: AstraZeneca, Abbvie
Jeremy S. Abramson, MD, MMSc
Director, Center for Lymphoma
Massachusetts General Hospital
Boston, MA
Dr. Abramson has reported the following relevant financial relationships or relationships with ineligible companies of any amount during the past 24 months:
Research support: BMS, Celgene, Cellectis, Genentech, Merck, Mustang Bio, Regeneron, Seagen, Takeda
Consulting fees: AbbVie, ADC Therapeutics, Astra-Zeneca, BeiGene, BMS, Celgene, Cellectar, Foresight Diagnostics, Genentech, Gilead, Interius, Lilly, Novartis, Roche, Seagen
Reviewers/Content Planners/Authors:
- Tim Person has no relevant relationships to disclose.
- Jocelyn Timko has no relevant relationships to disclose.
- Brian P. McDonough, MD, FAAFP, has no relevant relationships to disclose.
Learning Objectives
After participating in this educational activity, participants should be better able to:
- Apply clinical trial findings to guideline-concordant treatment planning for patients with CLL/SLL and MCL across all lines of therapy
- Analyze evolving clinical trial evidence with potential to inform updates to practice guidelines in CLL/SLL and MCL 
Target Audience
This activity has been designed to meet the educational needs of hematologists/hematology oncologists, medical oncologists, bone marrow transplantation specialists, pathologists, nurses, pharmacists, and other hematology/oncology healthcare professionals involved in the treatment of patients with hematologic malignancies.
Accreditation and Credit Designation Statements
In support of improving patient care, Global Learning Collaborative (GLC) is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.
Global Learning Collaborative (GLC) designates this enduring activity for a maximum of 0.5 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Global Learning Collaborative (GLC) designates this activity for 0.5 nursing contact hour(s). Nurses should claim only the credit commensurate with the extent of their participation in the activity.
Global Learning Collaborative (GLC) designates this activity for 0.5 contact hour(s)/0.05 CEUs of pharmacy contact hour(s).

The Universal Activity Number for this program is JA0006235-0000-25-012-H01-P. This learning activity is knowledge-based. Your CE credits will be electronically submitted to the NABP upon successful completion of the activity. Pharmacists with questions can contact NABP customer service (custserv@nabp.net).
Global Learning Collaborative (GLC) has been authorized by the American Academy of PAs (AAPA) to award AAPA Category 1 CME credit(s) for activities planned in accordance with AAPA CME Criteria. This activity is designated for 0.5 AAPA Category 1 CME credit(s). Approval is valid until 1/23/2026. PAs should claim only the credit commensurate with the extent of their participation in the activity.
Provider(s)/Educational Partner(s)

Prova Education designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties. Prova Education's methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the best education in the most impactful manner and to verify its results with progressive outcomes research.
Commercial Support
This activity is supported by independent educational grants from Merck Sharp & Dohme, LLC, a subsidiary of Merck & Co., Inc. and Lilly USA, LLC
Disclaimer
The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of GLC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience, and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to access a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.
Reproduction Prohibited
Reproduction of this material is not permitted without written permission from the copyright owner.
System Requirements
- Supported Browsers (2 most recent versions):
- - Google Chrome for Windows, Mac OS, iOS, and Android
  - Apple Safari for Mac OS and iOS
  - Mozilla Firefox for Windows, Mac OS, iOS, and Android
  - Microsoft Edge for Windows
- Recommended Internet Speed: 5Mbps+
Publication Dates
Release Date: 01/23/2025
Expiration Date: 01/23/2026