What are the mechanisms that are suspect for increasing incidence of osteonecrosis of the jaw in those taking bisphosphonates? Is this a significant risk? Dr. John Carey, consultant physician in internal medicine and rheumatology at Galway University Hospitals, reviews the evidence potentially modifying or increasing the risk of patients developing osteonecrosis of the jaw if they take bisphosphonates. Do patients need an oral exam before they begin taking bisphosphonates? Dr. Lee Freedman hosts.