For patients with severe hepatic malignancy, attempts to cure their illness are rarely, if ever, successful. We're learning, however, that a more aggressive surgical approach may extend survival rates well beyond those of our previous techniques. Dr. Alan Hemming, professor of surgery and chief of transplantation and hepatobiliary surgery at the University of Florida College of Medicine, details his pursuit of novel measures to surgically address severe hepatic malignancies with host Dr. Mark Nolan Hill.