ACC.25 – Diego Sadler reviews the results from the API-CAT study, which examined the efficacy and safety of low-dose apixaban versus full dose in patients with cancer-associated VTE. According to Sadler, it is good news for this patient population that the lower dose does not appear to be less effective and has a good safety signal.
Low-dose apixaban noninferior to full dose in cancer-associated VTE

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Overview
Educational information
This video was recorded during the ACC.25 Scientific Session Chicago, IL, USA.
Faculty
Diego Sadler, MD is section head Cardio-Oncology at the department of Cardiovascular Medicine AT Cleveland Clinic Florida in Weston, FL, USA. He is chair-elect of the ACC Cardio-Oncology Council.
Disclaimer
This recording was developed under auspices of PACE-CME. Views expressed in the recording are those of the presenter and do not necessarily reflect the views of PACE-CME.
Release date: 18 April 2025
The findings of this study were simultaneously published in N Engl J Med.
The information and data provided in this program were updated and correct at the time of its development, but may be subject to change.
Overview
ACC.25 – Diego Sadler reviews the results from the API-CAT study, which examined the efficacy and safety of low-dose apixaban versus full dose in patients with cancer-associated VTE. According to Sadler, it is good news for this patient population that the lower dose does not appear to be less effective and has a good safety signal.
Educational information
This video was recorded during the ACC.25 Scientific Session Chicago, IL, USA.
Faculty
Diego Sadler, MD is section head Cardio-Oncology at the department of Cardiovascular Medicine AT Cleveland Clinic Florida in Weston, FL, USA. He is chair-elect of the ACC Cardio-Oncology Council.
Disclaimer
This recording was developed under auspices of PACE-CME. Views expressed in the recording are those of the presenter and do not necessarily reflect the views of PACE-CME.
Release date: 18 April 2025
The findings of this study were simultaneously published in N Engl J Med.
The information and data provided in this program were updated and correct at the time of its development, but may be subject to change.
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