ACC.25 – In the ADVANCE-HTN trial, researchers evaluated the efficacy and safety of lorundrostat - a novel aldosterone synthase inhibitor - as an add-on therapy for patients with uncontrolled and treatment-resistant hypertension. Commenting on the findings, Dr. Gina Lundberg stated: “I think this is just one more tool in the toolkit when it comes to treating resistant hypertension.”
Lorundrostat lowers BP in uncontrolled and treatment-resistant hypertension

Ready to Claim Your Credits?
You have attempts to pass this post-test. Take your time and review carefully before submitting.
Good luck!
Overview
Educational information
This video was recorded during the ACC.25 Scientific Session Chicago, IL, USA.
Faculty
Gina Price Lundberg is a cardiologist at Emory Clinic in East Cobb and at Emory Saint Joseph Women's Center in Atlanta, GA, USA. She is associate professor at Emory University and clinical director of the Emory Womens Cardiovascular Health Center. She is chair of the ACC Women in Cardiology (WIC) Leadership Council and a member of the AHA Clinical Cardiology Leadership Council.
Disclaimer
This recording was developed under auspices of PACE-CME. Views expressed in the recording are those of the presenter and do not necessarily reflect the views of PACE-CME.
Release date: 18 April 2025
The findings of Advance-HTN have been accepted for publication in the New Engl J Med.
The information and data provided in this program were updated and correct at the time of its development, but may be subject to change.
Overview
ACC.25 – In the ADVANCE-HTN trial, researchers evaluated the efficacy and safety of lorundrostat - a novel aldosterone synthase inhibitor - as an add-on therapy for patients with uncontrolled and treatment-resistant hypertension. Commenting on the findings, Dr. Gina Lundberg stated: “I think this is just one more tool in the toolkit when it comes to treating resistant hypertension.”
Educational information
This video was recorded during the ACC.25 Scientific Session Chicago, IL, USA.
Faculty
Gina Price Lundberg is a cardiologist at Emory Clinic in East Cobb and at Emory Saint Joseph Women's Center in Atlanta, GA, USA. She is associate professor at Emory University and clinical director of the Emory Womens Cardiovascular Health Center. She is chair of the ACC Women in Cardiology (WIC) Leadership Council and a member of the AHA Clinical Cardiology Leadership Council.
Disclaimer
This recording was developed under auspices of PACE-CME. Views expressed in the recording are those of the presenter and do not necessarily reflect the views of PACE-CME.
Release date: 18 April 2025
The findings of Advance-HTN have been accepted for publication in the New Engl J Med.
The information and data provided in this program were updated and correct at the time of its development, but may be subject to change.
Title
Share on ReachMD
CloseProgram Chapters
Segment Chapters
Playlist:
Recommended
IgG4-RD Case Conversations: Diagnosing Pancreaticobiliary Manifestations and Ruling Out Malignancy
Spinal Muscular Atrophy: Optimizing the Management of Adults in the Era of Disease-Modifying Therapies
Diagnosis and Management of Metastatic PDAC
New Horizons: Unraveling Novel Therapies for Enhanced Cardiovascular Outcomes in Patients With Heart Failure
A Practical Guide to Prescribing in HF
Clinical Conundrums in ARIA: Nuances of Microhemorrhages when Evaluating an MRI for ARIA
Clinical Conundrums in ARIA: Differential Diagnoses and Potential Pitfalls in ARIA Evaluation
The Importance of PD-L1 Testing: Shaping the Future of Treatment in ESCC
We’re glad to see you’re enjoying ReachMD…
but how about a more personalized experience?