ACC.25 – Gina Lundberg discusses the results of Advance-HTN, in which the efficacy and safety of add-on lorundrostat, a novel aldosterone synthase inhibitor, was examined in patients with uncontrolled and treatment-resistant hypertension. She says: “I think this is just one more tool in the toolkit when it comes to treating resistant hypertension.”
Lorundrostat lowers BP in uncontrolled and treatment-resistant hypertension

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Overview
Educational information
This video was recorded during the ACC.25 Scientific Session Chicago, IL, USA.
Faculty
Gina Price Lundberg is a cardiologist at Emory Clinic in East Cobb and at Emory Saint Joseph Women's Center in Atlanta, GA, USA. She is associate professor at Emory University and clinical director of the Emory Womens Cardiovascular Health Center. She is chair of the ACC Women in Cardiology (WIC) Leadership Council and a member of the AHA Clinical Cardiology Leadership Council.
Disclaimer
This recording was developed under auspices of PACE-CME. Views expressed in the recording are those of the presenter and do not necessarily reflect the views of PACE-CME.
Release date: 18 April 2025
The findings of Advance-HTN have been accepted for publication in the New Engl J Med.
The information and data provided in this program were updated and correct at the time of its development, but may be subject to change.
Overview
ACC.25 – Gina Lundberg discusses the results of Advance-HTN, in which the efficacy and safety of add-on lorundrostat, a novel aldosterone synthase inhibitor, was examined in patients with uncontrolled and treatment-resistant hypertension. She says: “I think this is just one more tool in the toolkit when it comes to treating resistant hypertension.”
Educational information
This video was recorded during the ACC.25 Scientific Session Chicago, IL, USA.
Faculty
Gina Price Lundberg is a cardiologist at Emory Clinic in East Cobb and at Emory Saint Joseph Women's Center in Atlanta, GA, USA. She is associate professor at Emory University and clinical director of the Emory Womens Cardiovascular Health Center. She is chair of the ACC Women in Cardiology (WIC) Leadership Council and a member of the AHA Clinical Cardiology Leadership Council.
Disclaimer
This recording was developed under auspices of PACE-CME. Views expressed in the recording are those of the presenter and do not necessarily reflect the views of PACE-CME.
Release date: 18 April 2025
The findings of Advance-HTN have been accepted for publication in the New Engl J Med.
The information and data provided in this program were updated and correct at the time of its development, but may be subject to change.
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