ReachMD Faculty
Public Profile
Manish A. Shah, MD FASCO

- Bartlett Family Professor
- Gastrointestinal Oncology
- Chief, Solid Tumor Oncology
- Weill Cornell Medicine
Dr. Shah's clinical and academic focus lies in the care of patients with cancers of the gastrointestinal tract. Gastrointestinal malignancies are among the most common cancers in the United States and around the globe. Patients with cancers of the GI tract often require expertise across a broad range of disciplines. We are committed to providing personalized and coordinated care in an effort to maximize patient outcomes while minimizing potential side effects of therapy. Advancing the treatment of patients with gastrointestinal malignancies is central to the mission of the Gastrointestinal Oncology Program within the Division of Hematology and Medical Oncology and the Center for Advanced Digestive Care. Additionally, by improving our understanding of the biology of these diseases, including genetic and environmental risks, the role of inflammation and the tumor microenvironment in the development and progression of disease, we hope to improve our ability to prevent, diagnose, and treat these complex diseases.
Dr. Shah graduated from Johns Hopkins University in 1991 with a Bachelor's of Science degree in Biomedical Engineering, and from Harvard Medical School/MIT Health Sciences and Technology program in 1996, graduating magna cum laude, with a Medical Doctorate degree. He completed his Internal Medicine Residency training at Duke University Medical Center in 1999, and his Medical Oncology Fellowship at Memorial Sloan-Kettering Cancer Center in 2001, also serving as Chief Oncology Fellow. He is the recipient of several awards including the American Society of Clinical Oncology Young Investigator and Career Development Awards. He was recruited from Memorial Sloan Kettering Cancer Center to Direct the Gastrointestinal Oncology Program within the Division of Hematology and Medical Oncology and the Center for Advanced Digestive Care at Weill Cornell Medical College / New York-Presbyterian Hospital.
Dr. Shah is a national and international thought leader in drug development and the treatment of gastrointestinal malignancies. He is a distinguished peer-review funded investigator and has led several Phase I, II and III clinical trials in patients with advanced gastric cancer. Dr. Shah is also the Director of the Gastrointestinal Oncology Research Laboratory at Weill Cornell Medical College. His areas of translational research interests are in improving our understanding of cancers of the upper GI tract as well as hereditary gastrointestinal malignancies. He is interested in power of genomic evaluations of malignancy and how the environment and personal risks can impact the genetic causes of malignancy. He is a peer-reviewer for NIH and NCI research funding, and a reviewer for several high impact journals including the Journal of the American Medical Association, Journal of Clinical Oncology, Annals of Surgery, Annals of Surgical Oncology, Clinical Cancer Research and Gastroenterology. Dr. Shah is also the Editor for The Management of Complex Cases in Gastrointestinal Oncology Case Series for the Journal Of Gastrointestinal Oncology and the Series Editor for the Dx/RX: Oncology Series published by Jones and Bartlett Publishers. He has authored several books including Dx/Rx: Upper Gastrointestinal Malignancies: Cancers of the Stomach and Esophagus, as well as 100 Questions and Answers about Stomach Cancer. He is a member of the American Society of Clinical Oncology (serving as a Cancer Education Committee Member), American Association of Cancer Research, and the American Gastroenterology Association. In addition, Dr. Shah is Chair of the Scientific Advisory Board for the DeGregorio Family Foundation for Stomach and Esophageal Cancer Education and Research.
Dr. Shah graduated from Johns Hopkins University in 1991 with a Bachelor's of Science degree in Biomedical Engineering, and from Harvard Medical School/MIT Health Sciences and Technology program in 1996, graduating magna cum laude, with a Medical Doctorate degree. He completed his Internal Medicine Residency training at Duke University Medical Center in 1999, and his Medical Oncology Fellowship at Memorial Sloan-Kettering Cancer Center in 2001, also serving as Chief Oncology Fellow. He is the recipient of several awards including the American Society of Clinical Oncology Young Investigator and Career Development Awards. He was recruited from Memorial Sloan Kettering Cancer Center to Direct the Gastrointestinal Oncology Program within the Division of Hematology and Medical Oncology and the Center for Advanced Digestive Care at Weill Cornell Medical College / New York-Presbyterian Hospital.
Dr. Shah is a national and international thought leader in drug development and the treatment of gastrointestinal malignancies. He is a distinguished peer-review funded investigator and has led several Phase I, II and III clinical trials in patients with advanced gastric cancer. Dr. Shah is also the Director of the Gastrointestinal Oncology Research Laboratory at Weill Cornell Medical College. His areas of translational research interests are in improving our understanding of cancers of the upper GI tract as well as hereditary gastrointestinal malignancies. He is interested in power of genomic evaluations of malignancy and how the environment and personal risks can impact the genetic causes of malignancy. He is a peer-reviewer for NIH and NCI research funding, and a reviewer for several high impact journals including the Journal of the American Medical Association, Journal of Clinical Oncology, Annals of Surgery, Annals of Surgical Oncology, Clinical Cancer Research and Gastroenterology. Dr. Shah is also the Editor for The Management of Complex Cases in Gastrointestinal Oncology Case Series for the Journal Of Gastrointestinal Oncology and the Series Editor for the Dx/RX: Oncology Series published by Jones and Bartlett Publishers. He has authored several books including Dx/Rx: Upper Gastrointestinal Malignancies: Cancers of the Stomach and Esophagus, as well as 100 Questions and Answers about Stomach Cancer. He is a member of the American Society of Clinical Oncology (serving as a Cancer Education Committee Member), American Association of Cancer Research, and the American Gastroenterology Association. In addition, Dr. Shah is Chair of the Scientific Advisory Board for the DeGregorio Family Foundation for Stomach and Esophageal Cancer Education and Research.