New Evidence on Weekday Sleep Duration and eGDR

A weekday sleep duration and eGDR analysis shows an inverted U-shaped association between habitual weekday sleep and estimated glucose disposal rate (eGDR). The highest eGDR was observed at an optimal duration of about 7 hours 18 minutes of weekday sleep.

Analyses were based on 23,475 NHANES participants, with 10,817 individuals contributing weekend sleep-duration data. For weekday sleep, the report described an inverted U-shaped pattern: below about 7 hours 18 minutes, longer nightly sleep was associated with higher eGDR, while above that point, longer nightly sleep was associated with lower eGDR. The association above the threshold appeared stronger in women and in adults aged 40–59.

Weekend catch-up sleep showed different directional associations depending on weekday sleep relative to the optimal threshold. Among those below the weekday threshold, weekend catch-up in the 1–2 hour range was linked with higher eGDR compared with no catch-up. In contrast, among those above the weekday threshold, the >2 hour catch-up group was linked with lower eGDR after adjustment for potentially influential factors.

Key Takeaways:

• The report described an inverted U-shaped association between weekday sleep and eGDR, with a reported peak around 7 hours 18 minutes.
• Weekend catch-up sleep associations were described as differing depending on whether weekday sleep was below versus above the reported optimal threshold.