A recent study has identified a connection between asthma and memory difficulties in children, marking the first time these two conditions have been formally linked. Published in JAMA Network Open, the findings suggest that children with asthma may have a reduced ability to remember specific events, known as episodic memory. This discovery encourages healthcare providers to consider asthma not only as a respiratory condition but also as one that may affect cognitive development, particularly in children diagnosed at an early age.
The study, which analyzed data from 473 children in the United States who developed asthma early in life, found that those with asthma scored lower on episodic memory tests than children without the condition. These assessments measured the children’s ability to recall details about daily events, such as who was present and their own emotional responses. The data suggest that children who develop asthma at a younger age may experience more significant memory challenges. Although researchers did not determine the exact mechanisms behind these memory deficits, they hypothesized that chronic inflammation and interruptions in oxygen flow to the brain from recurrent asthma attacks could be contributing factors.
Asthma affects about 260 million people globally, including 5.4 million in the UK, with a substantial portion of cases diagnosed in childhood. According to Nicholas Christopher-Hayes, one of the study’s lead authors, childhood is a critical phase for memory and cognitive growth. In children with asthma, however, these developmental gains may progress more slowly. The researchers also noted that asthma-related memory deficits might elevate the risk of cognitive challenges in adulthood, potentially increasing susceptibility to more severe conditions, such as dementia.
While the study reveals a possible link between asthma and memory issues, experts, including respiratory medicine professor Nick Hopkinson, stress that further investigation is needed to understand the underlying causes. Factors like early-life stress and socioeconomic deprivation, both associated with more severe asthma, could also play a role in affecting memory. Hopkinson suggested that asthma-related inflammation might influence multiple bodily systems, indirectly impacting memory function. These findings highlight the importance of early asthma intervention, effective symptom management, and addressing social factors that may exacerbate both asthma severity and cognitive difficulties.