Increased Cardiovascular Risk in Postpartum Mothers of Twins

Recent findings reveal that mothers of twin pregnancies face a significantly increased risk of heart disease within the first year postpartum, suggesting a critical need for enhanced postnatal care.
Significance
This information is crucial for healthcare providers to tailor postpartum care and monitoring for mothers of twins, aiming to reduce the risk of cardiovascular complications.
Quick Summary
A study published in the European Heart Journal indicates that mothers of twins are at an elevated risk of heart disease within a year after childbirth, especially if they experienced hypertension during pregnancy. This research, utilizing data from over 36 million U.S. hospital deliveries, reveals that mothers of twins with normal blood pressure are twice as likely to be hospitalized for cardiovascular diseases compared to mothers of singletons. For those with twins and hypertensive disorders, the risk exceeds eightfold.
Stats and Figures
1,105.4 per 100,000: The rate of cardiovascular disease hospital readmissions for twin pregnancies within a year postpartum.
734.1 per 100,000: The rate of cardiovascular disease hospital readmissions for singleton pregnancies within a year postpartum.
8.21: Adjusted hazard ratio for cardiovascular disease in mothers of twins with hypertensive disease compared to singletons.
Learning Objectives
Understand the increased cardiovascular risks associated with twin pregnancies and the importance of tailored postpartum care.
The Complexity of Twin Pregnancies
Twin pregnancies demand more from maternal cardiovascular systems. Twin pregnancies significantly increase the workload on a mother's cardiovascular system compared to singleton pregnancies.
As noted by Dr. Ruby Lin, a maternal-fetal medicine fellow at Rutgers, "The maternal heart works harder for twin pregnancies than for singleton pregnancies, and it takes weeks for the maternal heart to return to its pre-pregnancy state." This heightened demand can increase the risk of cardiovascular complications post-delivery.
Significant physiological changes during pregnancy, such as increased blood volume and cardiac output, are more pronounced in twin pregnancies. This amplifies cardiovascular strain, which may not fully resolve immediately postpartum, thereby raising disease risk.
Understanding Risk Factors
Identifying and managing hypertension during pregnancy is crucial. Hypertension during twin pregnancies considerably elevates the risk of cardiovascular diseases postpartum.
Research conducted by Professor Cande Ananth and colleagues found that among those with hypertension during twin pregnancies, the risk of postpartum cardiovascular disease increased significantly, with an adjusted hazard ratio of more than eight times that of singletons.
This observation underscores the necessity for healthcare providers to carefully monitor blood pressure and manage hypertensive conditions promptly during pregnancy, particularly in twin pregnancies. Such management can have a profound impact on postpartum health outcomes.
Implications for Postpartum Care
Postpartum care should be extended and specialized for mothers of twins. Enhanced and prolonged follow-up care postpartum is necessary for mothers of twins to mitigate cardiovascular risks.
As highlighted by experts in the field, mothers of twins often face increased cardiovascular risks that necessitate ongoing medical supervision post-delivery. This is crucial to address vulnerabilities that persist even after achieving normal blood pressure postpartum.
The concept of the 'fourth trimester' has gained attention as being critical for monitoring heart health. This period is an opportunity to implement interventions that can significantly influence the long-term cardiovascular health of mothers. Collaboration among specialties such as obstetrics and cardiology is essential for optimizing maternal care during this time.
Towards Improved Maternal Health Outcomes
Awareness and research are key to improving maternal cardiovascular health. Increasing awareness and research into maternal cardiovascular health, especially for high-risk groups like mothers of twins, is vital for enhancing health outcomes.
Dr. Katherine Economy emphasizes that understanding the specific cardiovascular risks associated with twin pregnancies sheds light on a major gap in maternal health knowledge. This understanding can direct resource allocation and healthcare strategies to better serve this high-risk group.
Continued research and awareness of cardiovascular risks are essential for formulating targeted interventions. Such strategies will not only improve immediate postpartum health but contribute to lowering overall maternal mortality related to cardiovascular diseases.
Citations
Ananth, C. V., & Lin, R. (2025). Hospitalization for cardiovascular disease in the year after delivery of twin pregnancies. European Heart Journal, 45(2), 123-130.
Williams, A. F., & Economy, K. (2025). Double double, future trouble? Opportunities for cardio-obstetric collaboration to reduce future cardiovascular events following twin pregnancies. European Heart Journal, 45(2), 131-139.