Hidradenitis Suppurativa: Unraveling Its Global Prevalence and Implications

Hidradenitis suppurativa, a persistent yet underestimated skin condition, is now recognized as more widespread than previously understood.

Recent global studies on hidradenitis suppurativa prevalence have revealed that the estimated global prevalence ranges from 0.99% to 2.5%, although estimates vary widely by methodology and population (for example, claims datasets versus clinician-diagnosed cohorts), and this range reflects upper-end findings from select analyses rather than a settled global figure.

While higher than many earlier reports, these figures likely reflect improved ascertainment and methodological differences rather than confirmed temporal increases, and they underscore the persistent underrecognition of this chronic inflammatory disease.

Demographic analyses indicate these shared factors are associated with differences in observed prevalence; notably, female sex, age, and race are linked to variability across populations. The role of demographic factors in HS prevalence is evident as recent studies highlight female demographic trends.

Key Takeaways:

• HS prevalence is higher than previously thought, reshaping clinical approaches.
• Demographic insights highlight actionable factors improving patient identification.
• Enhanced understanding of prevalence supports improved case finding, earlier staging, and more timely referral.