Emerging Role of Nutraceuticals in Asthma Management: Integrating Beetroot Bioactives

According to the 2025 GINA guidelines, nutraceuticals (bioactive food-derived compounds with health benefits) are emerging as a dynamic component in enhancing asthma management amid rising disease prevalence and treatment complexity.

Recent findings, detailed in the Connecting the Dots: Beetroot and Asthma study, are revealing how beetroot's betalains and nitrates can modulate inflammatory cascades (inflammatory pathways) and support traditional anti-inflammatory strategies in asthma management.

Building on this, the integration of beetroot-derived nutrients with standard anti-inflammatory therapies is adding another layer to strategies aimed at controlling airway inflammation and improving symptom management.

Continuing the discussion on oxidative stress, nutraceuticals loaded with antioxidant compounds such as polyphenols and betalains are crucial in scavenging free radicals that perpetuate airway remodeling and hyperresponsiveness, as discussed in an editorial commentary in Frontiers on nutraceutical modulation of oxidative stress.

As previously mentioned in the MDPI study, individual beetroot bioactives can vary in their effects—offering bronchodilatory support in some patients while posing potential irritant risks in others—underscoring the importance of tailoring regimens to patient profiles and close clinical monitoring.

Key Takeaways:

• Nutraceuticals such as beetroot are showing promise in enhancing anti-inflammatory effects in asthma management.
• Targeting oxidative stress with antioxidant-rich nutraceuticals can complement traditional therapies to protect airway integrity.
• Individual variability in beetroot bioactives necessitates personalized assessment and monitoring.
• Nutraceuticals should serve as adjuncts to, not replacements for, established asthma treatments.