Dual 1550/1927-nm Laser System Shows Favorable Outcomes in Skin of Color

Non-ablative fractional laser treatments are widely used for dyschromia, scarring, and photoaging, yet data in patients with skin of color remain comparatively limited. In a review published online in Lasers in Surgery and Medicine, the authors evaluated the safety and efficacy of a dual 1550-nm erbium glass fiber and 1927-nm thulium fiber laser system in individuals with Fitzpatrick skin types (FSTs) III–VI.

The authors analyzed 15 clinical studies assessing outcomes with the 1550-nm and/or 1927-nm wavelengths in patients with skin of color. Across heterogeneous study designs, consistent clinical improvement was reported with the 1550-nm wavelength for scarring and melasma, and with the 1927-nm wavelength for melasma and photoaging.

Rates of post inflammatory hyperpigmentation (PIH) varied among studies. In investigations directly comparing device parameters, lower pulse energy and/or treatment density were associated with reduced PIH rates. Histologic findings across selected studies demonstrated dermal remodeling and reductions in melanin following treatment.

The authors conclude that the 1550/1927-nm dual-laser system is safe and effective in patients with skin of color. They also note that parameter adjustments—specifically reduced pulse energy and density—may mitigate adverse effects. However, they emphasize the need for additional research, particularly among patients with FST VI and in studies evaluating the 1927-nm wavelength.