Could methotrexate application at the time of silicone oil placement and again after silicone oil removal improve outcomes in high-risk PVR cases undergoing retinal detachment repair? In this episode of Clinical Minute: Retina, host Maria Berrocal, MD, sits down with Maggie Runner, MD, to discuss a study evaluating a modified methotrexate protocol for complex retinal detachment repair. They review which patients may benefit most, practical dosing strategies, and how this approach could influence management of the most high-risk patients.
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