In this video brief, Dr. Jhaveri reviews additional safety data from TROPION-Breast02 showing that exposure-adjusted rates of treatment-related adverse events were lower with first-line Dato-DXd vs chemotherapy in patients with advanced TNBC who are not eligible for immunotherapy. She also reviews the study design of TROPION-Breast06, a phase 3b trial evaluating Dato-DXd prior to chemotherapy in endocrine-refractory HR+/HER2- disease with the potential to move Dato-DXd earlier in the treatment paradigm.
Additional Safey Data From TROPION-Breast02 and Study Design of TROPION-Breast06

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Overview
Provider(s)/Educational Partner(s)

Global Learning Collaborative (GLC) designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties. GLC’s methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the best education in the most impactful manner and to verify its results with progressive outcomes research.
Commercial Support
This activity is supported by independent educational grants from AstraZeneca Pharmaceuticals, L.P. and Daiichi Sankyo, Inc.
Overview
In this video brief, Dr. Jhaveri reviews additional safety data from TROPION-Breast02 showing that exposure-adjusted rates of treatment-related adverse events were lower with first-line Dato-DXd vs chemotherapy in patients with advanced TNBC who are not eligible for immunotherapy. She also reviews the study design of TROPION-Breast06, a phase 3b trial evaluating Dato-DXd prior to chemotherapy in endocrine-refractory HR+/HER2- disease with the potential to move Dato-DXd earlier in the treatment paradigm.
Provider(s)/Educational Partner(s)

Global Learning Collaborative (GLC) designs and executes continuing education founded on evidence-based medicine, clinical need, gap analysis, learner feedback, and more. Our mission is to serve as an inventive and relevant resource for clinical content and educational interventions across a broad spectrum of specialties. GLC’s methodology demonstrates a commitment to continuing medical education and the innovative assessment of its effects. Our goal is clear—to develop and deliver the best education in the most impactful manner and to verify its results with progressive outcomes research.
Commercial Support
This activity is supported by independent educational grants from AstraZeneca Pharmaceuticals, L.P. and Daiichi Sankyo, Inc.
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