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Can Artificial Intelligence Predict the Risk of Dying in the Years Following a Hip Fracture?

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09/21/2023
scienmag.com

A new study published in the Journal of Orthopaedic Research indicates that an artificial intelligence–based model trained on basic blood and lab test data as well as basic demographic data can predict a patient’s risk of death within 1-, 5-, and 10-years of experiencing a hip fracture.

In the analysis of 3,751 hip fracture patient records from two in‐hospital database systems at the Beth Israel Deaconess Medical Center in Boston, the 1‐year mortality rate for all patients was 21% and for those aged 80 years and older was 29%. After assessing 10 different machine learning classification models, investigators found that the LightGBM model had the most accurate 1‐year mortality prediction performance. Age, blood sugar levels, certain red blood cell characteristics, white blood cell levels, urea nitrogen levels, platelet count, calcium levels, and blood clotting time were factors with the highest predictive power. Most of these were also in the top 10 features of the LightGBM 5‐ and 10‐year mortality prediction models.

“Our models show that certain biomarkers can be particularly useful in characterizing the risk of poor outcomes following hip fractures,” said corresponding author George Asrian, of the University of Pennsylvania.

URL upon publication: https://onlinelibrary.wiley.com/doi/10.1002/jor.25675

Additional Information
NOTE: 
The information contained in this release is protected by copyright. Please include journal attribution in all coverage. For more information or to obtain a PDF of any study, please contact: Sara Henning-Stout, newsroom@wiley.com.

About the Journal
The Journal of Orthopaedic Research®, a publication of the Orthopaedic Research Society (ORS), is the forum for the rapid publication of high quality reports of new information on the full spectrum of orthopaedic research, including life sciences, engineering, translational, and clinical studies.

About Wiley
Wiley is a knowledge company and a global leader in research, publishing, and knowledge solutions. Dedicated to the creation and application of knowledge, Wiley serves the world’s researchers, learners, innovators, and leaders, helping them achieve their goals and solve the world’s most important challenges. For more than two centuries, Wiley has been delivering on its timeless mission to unlock human potential. Visit us at Wiley.com. Follow us on Facebook, Twitter, LinkedIn and Instagram.



Journal

Journal of Orthopaedic Research®

Article Title

Machine Learning-Based Mortality Prediction in Hip Fracture Patients Using Biomarkers

Article Publication Date

20-Sep-2023

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