Bladders, Breakthroughs, and Bold New Therapies: Key Updates at AUA 2025

Announcer:
You’re listening to Clinician’s Roundtable on ReachMD. On this episode, Dr. Wayne Kuang will discuss key updates being presented at the 2025 American Urological Association Annual Meeting. Dr. Kuang is the CEO of MD for Men in Albuquerque, New Mexico and the Founder of the ManVsProstate campaign. Let’s hear from him now.

Dr. Kuang:
The key updates that all of us are looking forward to is what I call the magic of micro-conversations. What do I mean by that? We’re getting to see old friends, old mentors, old teachers, old colleagues, and begin to communicate and have those small conversations over coffee or in the hallway and catch up about how can we be better and do better as urologists in our clinics, in the operating room, and in our healthcare systems.

Looking through the lens of bladder health, this is an exciting time. We have now entered into the golden era of diagnostics and better therapeutics for BPH and BPO, as well as for bladder health, and so this is exciting times. We want every man to become the best version of themselves—incontinence free and catheter free. As we preserve bladder health, we prevent late-stage disease, and we help end the polypharmacy epidemic. And so the abstract count is indicative of what we’re thinking. There’s about 39 abstracts on BPH and BPO; about 41 on overactive bladder, stage 2, urgency, urge incontinence, and stage 3; there’s nine abstracts on stage 4 retention; and one on detrusor underactivity, stage 5.

The mindset is shifting. The prostate is being asked to step aside and make room on the red carpet for the bladder to have a seat and stand with the prostate in the spotlight, which is going to help everyone: patients, healthcare systems, urologists, and, of course, bladders.

In the plenary sessions on Sunday, there’s four main elements: a man’s vitality, economic sustainability, treatment durability, and the window of curability within which we can save more bladders. And so on that Sunday, Dr. Steven Kaplan, a visionary in BPH and BPO, is going to talk about prostatic stents, which he calls in the category of FITS—first-line interventional therapies, fantastic name—also known as TMIST. Is this new technology effective? Is it durable? When do we use it? How do we use it? Why do we use it? Great questions. And then Defender Kevin Zorn from Canada is going to talk about ejaculation-sparing techniques for surgery. Huge, right? For every man out there to preserve that critical element of a man’s vitality. And then the window of curability.

There’s two talks that are really exciting. One is from Brazil, Sao Paulo, and that’s Dr. Jose Truzzi. The title is Male Voiding Dysfunction: Beyond the Prostate. We need to start thinking holistically—beyond the prostate to the bladder, to the pelvic floor, to the urinary sphincter. We’re starting to expand our thoughts. And another talk from a pediatric urologist, Dr. Rosalyn Adam—this is an exciting talk because she’s going to talk about obstructive bladder disease—the molecular insights and therapeutic opportunities directly relatable to pediatrics, but also to us as we defend the bladders against obstructing prostates in the adult man.

Announcer:
That was Dr. Wayne Kuang discussing updates from the 2025 American Urological Association Annual Meeting. To access this and other episodes in our series, visit Clinician’s Roundtable on ReachMD.com, where you can Be Part of the Knowledge. Thanks for listening!