Some Forms of Childhood Malnutrition, Stunting May be Preventable With Vaccines: In Mice, Vaccination Prevents Gut Damage Linked to Toxin From Diarrhea-Causing Bacteria
https://reachmd.com/news/some-forms-of-childhood-malnutrition-stunting-may-be-preventable-with-vaccines-in-mice-vaccination-prevents-gut-damage-linked-to-toxin-from-diarrhea-causing-bacteria/2449536/
Diarrhea is no longer the killer it was in the mid-20th century, when an estimated 4.5 million children under age 5 died of it every year. While lifesaving oral rehydration therapy turned the tide, it doesn't prevent infection. Millions of children in low- and middle-income countries still endure r…
NHS ‘Nowhere Near Ready’ to Deliver New Alzheimer’s Drug, Doctors Say
https://reachmd.com/news/nhs-nowhere-near-ready-to-deliver-new-alzheimers-drug-doctors-say/2449535/
A reorganisation of NHS dementia care is needed to ensure UK patients can receive a groundbreaking drug that slows the progression of Alzheimer’s disease, doctors say.Detailed results from a clinical trial of lecanemab have confirmed that the drug reduces cognitive decline in patients with early-st…
Infectious Malaria Sporozoites Produced Without Mosquitoes Provide Progress for Malaria Vaccines
https://reachmd.com/news/infectious-malaria-sporozoites-produced-without-mosquitoes-provide-progress-for-malaria-vaccines/2449532/
Scientists from Sanaria Inc., and collaborators at multiple institutions published results in Nature reporting "In vitro production of infectious Plasmodium falciparum sporozoites." Sanaria Plasmodium falciparum (Pf) sporozoites (SPZ) vaccines have conferred the highest protective efficacy against…
Scientists Repurpose Cancer Immunotherapy Technique for Variant-Proof Covid Treatment
https://reachmd.com/news/scientists-repurpose-cancer-immunotherapy-technique-for-variant-proof-covid-treatment/2449528/
Scientists have adapted what is typically a cancer therapeutic technique, CAR-T cell therapy, for the purpose of eliminating the SARS-CoV-2 virus, according to a study. The team of scientists at the nonprofit biomedical research institution, The Jackson Laboratory for Genomic Medicine, led by Dery…
Tesis Biosciences Announces Proposed Study of Veterans and Civilians with Mild Traumatic Brain Injury
https://reachmd.com/news/tesis-biosciences-announces-proposed-study-of-veterans-and-civilians-with-mild-traumatic-brain-injury/2449527/
Company in preparation for formal FDA approval submission PHOENIX, Dec. 9, 2022 /PRNewswire/ -- Tesis Biosciences, the leader in targeted genetic sequencing, has announced a proposed study designed to develop molecular biomarkers to precisely differentiate mild traumatic brain injury (mTBI) from p…
Mount Sinai Study Links Molecular Changes to Long COVID a Year After Hospitalization
https://reachmd.com/news/mount-sinai-study-links-molecular-changes-to-long-covid-a-year-after-hospitalization/2449517/
Mount Sinai researchers have published one of the first studies to associate changes in blood gene expression during COVID-19 with the post-acute sequelae of SARS-CoV-2 infection, also known as “long COVID,” in patients more than a year after they were hospitalized with severe COVID-19. The find…
Vitamin D Supplements May Not Reduce Statin-Associated Muscular Pain
https://reachmd.com/news/vitamin-d-supplements-may-not-reduce-statin-associated-muscular-pain/2449515/
According to the Centers for Disease Control and Prevention (CDC), almost 2 in 5 adults in the United States have high cholesterol. High cholesterol does not produce any symptoms. However, it does increase the risk of cardiovascular conditions such as heart attack and stroke. Statins are the most…
Improve Memory As You Age by Eating More Flavonols, Study Says
https://reachmd.com/news/improve-memory-as-you-age-by-eating-more-flavonols-study-says/2449444/
CNN — Eating more flavonols, antioxidants found in many vegetables, fruits, tea and wine, may slow your rate of memory loss, a new study finds. The cognitive score of people in the study who ate the most flavonols declin…
ARNI favorably changes biomarkers of ECM homeostasis in HFpEF
https://reachmd.com/news/arni-favorably-changes-biomarkers-of-ecm-homeostasis-in-hfpef/2455777/
Literature - Cunningham JW, Claggett BL, O’Meara E, et al. - J Am Coll Cardiol 2020;76:503–14 Introduction and methods It has been suggested that changes in myocardial extracellular matrix (ECM) homeostasis occur during development of heart failure (HF) in patients with HFrEF and HFpEF. Chan…
Clinical phenotype-based HFpEF subgroups respond differently to aldosterone antagonist therapy
https://reachmd.com/news/clinical-phenotype-based-hfpef-subgroups-respond-differently-to-aldosterone-antagonist-therapy/2455611/
Literature - Cohen JB, Schrauben SJ, Zhao L et al., - JACC Heart Fail. 2020 doi: 10.1016/j.jchf.2019.09.009.Introduction and methodsTo date, no pharmacological therapies are known to improve patient outcomes in heart failure with preserved ejection fraction (HFpEF). The difficulty to find effective…