Interventions in Minimal Residual Disease Lead to Long-Term Melanoma Control
https://reachmd.com/news/interventions-in-minimal-residual-disease-lead-to-long-term-melanoma-control/2450720/
Cutaneous melanoma responds to targeted therapies (TT) and immune checkpoint inhibitors (ICI) in 3 phases, according to a recent review.1In the review, authors also found that TT and ICI can affect both melanoma cells and the tumor immune microenvironment, particularly in the middle of the 3 phases…
Spike Protein Implicated in Post-COVID-19 Memory Loss
https://reachmd.com/news/spike-protein-implicated-in-post-covid-19-memory-loss/2450685/
Summary: The spike protein that is responsible for COVID-19’s entry into cells could be responsible for post-COVID memory loss. Researchers identified the TLR4 receptor as a potential target for treating COVID-related memory loss.Source: INBEBPatients diagnosed with post-COVID-19 syndrome often exp…
Some Melanoma Patients with Leptomeningeal Disease Benefit from Novel Immunotherapy Delivery Approach
https://reachmd.com/news/some-melanoma-patients-with-leptomeningeal-disease-benefit-from-novel-immunotherapy-delivery-approach/2450712/
Leptomeningeal disease is a complication of cancer that occurs when cancer cells from primary tumors migrate into the cerebrospinal fluid (CSF) and leptomeninges, the outer lining of the brain and spinal cord. These cells can quickly spread throughout the CSF and cause a wide variety of neurologica…
Researchers Announce Findings from Landmark Clinical Trial for Pediatric Crohn’s Disease
https://reachmd.com/news/researchers-announce-findings-from-landmark-clinical-trial-for-pediatric-crohns-disease/2450675/
Michael Kappelman, MD, MPH, was the lead PI on the clinical trial, which followed nearly 300 children with Crohn’s to evaluate how their conditions changed in response to anti-TNF biologic treatments alone or in combination with a second immune suppressive medication. Michael Kappelman, MD,…
CHOP Researchers Reveal Complex Assembly Process Involved in DNA Virus Replication
https://reachmd.com/news/chop-researchers-reveal-complex-assembly-process-involved-in-dna-virus-replication/2450676/
--Study shows viral proteins utilize phase separation to coordinate complex process of replicating viral genomes and then encapsulating that DNA in a viral particle-- PHILADELPHIA, April 5, 2023 /PRNewswire/ -- In a twist on the question, "Which came first, the chicken or the egg?", scientists ha…
Clinical Trial may Change the Paradigm of Care for Patients with ALK-Driven High-Risk Neuroblastoma
https://reachmd.com/news/clinical-trial-may-change-the-paradigm-of-care-for-patients-with-alk-driven-high-risk-neuroblastoma/2450678/
In a significant step for the treatment of neuroblastoma, an international group of researchers led by Children's Hospital of Philadelphia (CHOP), Winship Cancer Institute of Emory University and the New Approaches to Neuroblastoma Therapy (NANT) Consortium has shown that the targete…
Study Examines Disparities in Women’s Pelvic Healthcare
https://reachmd.com/news/study-examines-disparities-in-womens-pelvic-healthcare/2450709/
MIAMI – Researchers at the University of Miami Miller School of Medicine are finding disparities in care for minority women with a group of disorders that affect female pelvic health.Dr. Raveen Syan, a urologist with UHealth’s Desai Sethi Urology Institute, said that up to 40 percent of women suffe…
Finding a Way to Combat Long COVID
https://reachmd.com/news/finding-a-way-to-combat-long-covid/2450687/
A new study has identified potential neurological biomarkers of long COVID-19 in nonhuman primates that may help physicians diagnose, monitor and treat this condition. Over 65 million people worldwide have developed long COVID after being infected with SARS-CoV-2, and cases are only becomin…
New Research Shows That Bacteria Get 'Hangry,' too
https://reachmd.com/news/new-research-shows-that-bacteria-get-hangry-too/2450681/
Have you ever been so hungry that you become angry, otherwise known as "hangry?" New research by Adam Rosenthal, PhD, assistant professor in the Department of Microbiology and Immunology, has found that some bacteria cells get hangry too, releasing harmful toxins into our bodies and making us sick.…
Can a Drug Used to Treat Liver Disease Help Prevent SARS-CoV-2 Infections & Lessen COVID-19 Severity?
https://reachmd.com/news/can-a-drug-used-to-treat-liver-disease-help-prevent-sars-cov-2-infections-lessen-covid-19-severity/2450689/
Credit: Unsplash/CC0 Public Domain SARS-CoV-2, the virus that causes COVID-19, attaches to a cellular receptor called angiotensin-converting enzyme 2 (ACE2), and activation of the farnesoid X recepto…