This is ReachMD, and you’re listening to Psoriasis: What’s Beneath the Surface, sponsored by Lilly.
From the ReachMD studios, I’m Dr. Matt Birnholz. On this episode, we caught up with Dr. Jerry Bagel, Director of the Psoriasis Treatment Center of Central New Jersey and Clinical Associate Professor of Dermatology at Mount Sinai School of Medicine. Dr. Bagel shared his thoughts on PASI scores for benchmarking psoriasis. Here’s Dr. Bagel now.
The National Psoriasis Foundation, as the medical advisory board, we treat-to-target 1% or less body surface area. Three percent or more or less is really what’s really important. I think PASI 100 is a good benchmark in regards to looking at data in clinical trials, and it’s important to see what percentage of people are 100% clear, but I think PASI 90 is still a very good benchmark for psoriasis. And then it really needs to be put in perspective. Let’s put it this way. If somebody has been on 4 different biologic agents, and they have been suffering with psoriasis for their whole life, and they have had it on 40% of their body, and they went on this new biologic agent, and they started with 25%, and they get down to 6 percent, which means they were a PASI of, let’s say, 75, that’s really a good result in that individual. On the other hand, somebody that’s never had a biologic agent before and they had it on 20% of their body, if they get down to 0, 1 or 2%, that’s also a really good percentage. So as much as I want to clear people, I think you really need to look at it from an individual perspective of who you’re treating, If you’re doing well on a biologic and you’re at 5%, maybe you can add a topical therapy in that case as well to get them to that 90% improvement or 95 or 100% improvement, but it’s not just about switching biologic agents all the time.
That was Dr. Bagel for sharing his views on PASI scores in psoriasis patients. For ReachMD, I’m Dr. Matt Birnholz. Thank you for listening!
The preceding program was sponsored by Lilly. Content for this series is produced and controlled by ReachMD. This series is intended for healthcare professionals only. To revisit any part of this discussion and to access other episodes in this series, visit ReachMD.com/beneaththesurface. Thank you for listening to ReachMD. Be Part of the Knowledge.