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What Causes Microsatellite Instability-High & Deficient Mismatch Repair?

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What Causes Microsatellite Instability-High & Deficient Mismatch Repair?

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What Causes Microsatellite Instability-High & Deficient Mismatch Repair?
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    How do germline mutations and somatic inactivation of mismatch repair genes result in the hereditary and sporadic forms of deficient mismatch repair?

    • Overview

      Microsatellite instability-high (MSI-H) tumors can result from deficient mismatch repair, which has two forms: hereditary and sporadic. But what causes these two forms to occur, and how are they different? That’s what this video breaks down.

      US-OVA-00156 04/20

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    Programs 4/15/21