The era of genomic medicine has barely begun, but visionaries are already looking past the genome to the proteome and the metabolome. Genes were only the beginning of a revolution in medicine. We talk to the chairman of a new National Academy of Sciences report spelling out the critical importance of the new science of toxicogenomics--in which the interactions between genes and the environment become central. Cigarette smoking is the classic example: 90 percent of smokers do NOT get lung cancer. It takes the combination of tobacco smoke and the right (or wrong) genes to cause the disease. How can practicing physicians equip themselves to practice genomic medicine? Join host Paul Raeburn to find out.