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Real-World Experience in Diagnosing and Managing PNH in Special Patient Populations

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Real-World Experience in Diagnosing and Managing PNH in Special Patient Populations

1.00 credits
60 minutes
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  • Overview

    In a “how I do it” clinical commentary, Dr. Jamile Shammo and Dr. Ilene Weitz share their real-world experience in the diagnosis and management of PNH in special patient populations. This case-based activity includes clinical scenarios and treatment strategies to improve patient outcomes. 

  • Provider(s)/Educational Partner(s)

    Sponsored by Rush University Medical Center and the Academy for Continued Healthcare Learning (ACHL).

  • Commercial Support

    Supported by educational grants from Alexion Pharmaceuticals, Inc and Apellis Pharmaceutical, Inc. 

  • Learning Objectives

    Upon completion of this activity, participants will be able to:

    • Discuss real-world experience in diagnosing and treating PNH in special patient populations
    • Formulate personalized treatment strategies considerate of patient risks, characteristics, complications, and preferences
    • Discuss coordination of care and clinical strategies amongst specialists to improve patient outcomes
  • Target Audience

    This educational activity is designed for hematologists, oncologists, pediatricians, OB/GYNs, and the multidisciplinary healthcare team who are involved in the care of patients with PNH.

  • Method of Participation

    This activity will take approximately 60 minutes to complete. To receive credit, participants are required to complete the pretest, view this internet enduring activity and complete the posttest and evaluation. To receive credit, 60% must be achieved on the posttest. A certificate will be immediately available. There is no fee to participate in the activity or for the generation of the certificate.

    For questions, contact Karen Catino at kcatino@achlcme.org

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Rush University Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    This activity is being presented without bias and with commercial support.

    Rush University Medical Center designates this internet enduring activity for a maximum of one (1) AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

    Rush University Medical Center designates this internet enduring activity for a maximum of one (1) nursing contact hour.

  • Disclosure of Conflicts of Interest

    Disclosure Policy:
    As a provider of continuing education, Rush University Medical Center requires everyone who has the ability to control or influence the content of an educational activity to disclose information about all of their financial relationships with ineligible companies within the prior 24 months.  There is no minimum financial threshold; individuals must disclose all financial relationships, regardless of the amount, with ineligible companies.  Individuals must disclose regardless of their view of the relevance of the relationship to the education.  Mechanisms are in place to identify and mitigate any potential conflicts of interest prior to the start of the activity. 

    The following financial relationships have been disclosed:

    Ilene Weitz, MD 
    Sources of Funding for Research:
    Consulting Agreements: Apellis Pharmaceutical, Inc., Norvartic, BioCryst Pharmaceuticals, Inc.
    Speakers' Bureau: Alexion Pharmaceuticals, Inc

    Discussion of Off-Label, Investigational, or Experimental Drug/Device Use: Potential use of eculizumab, ravulizumab, and pegcetacoplan during pregnancy; investigational therapies for the treatment of PNH: ABP 959, SB12, BCD-148, crovalimab, SKY59, RO7112689, tesidolumab, LFG316, pozelimab, REGN3918, zilucoplan, RA101495, nomacopan, VA576, coversin, cemdisiran, ALN-CC5, danicopan, ACH-4471, BCX9930, iptacopan, LNP023

    Jamile Shammo, MD
    Sources of Funding for Research: Abbvie, Alexion Pharmaceuticals, Inc., AstraZeneca , Bristol Meyers Squibb, Incyte, CTI BioPharma, Kartos Therapeutics, Novartis, Stemline Therapeutics, Inc.,
    Consulting Agreements: Alexion Pharmaceuticals, Inc., Apellis Pharmaceutical, Inc., Bristol Meyers Squibb, Incyte, Novartis, Sanofi, Takeda
    Stockholder: Abbvie, Baxter, Takeda
    Speakers' Bureau: Alexion Pharmaceuticals, Inc., Bristol Meyers Squibb, Incyte, Sanofi
    Other: DSMC for Apellis Pharmaceutical, Inc., NS Pharma, Inc. 

    Discussion of Off-Label, Investigational, or Experimental Drug/Device Use: Potential use of eculizumab, ravulizumab, and pegcetacoplan during pregnancy; investigational therapies for the treatment of PNH: ABP 959, SB12, BCD-148, crovalimab, SKY59, RO7112689, tesidolumab, LFG316, pozelimab, REGN3918, zilucoplan, RA101495, nomacopan, VA576, coversin, cemdisiran, ALN-CC5, danicopan, ACH-4471, BCX9930, iptacopan, LNP023 

    Staff and Reviewer Disclosures
    ACHL and Rush University Medical Center staff members and others involved with the planning, development, and review of the content for this activity have no relevant financial relationship(s) with ineligible companies to disclose.

  • Disclaimer

    The content for this activity was developed independently of the commercial supporter. All materials are included with permission. The opinions expressed are those of the faculty and are not to be construed as those of the publisher or grantor.

    This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Recommendations involving clinical medicine in a continuing medical education (CME/CE) activity must be based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the care of patients. All scientific research referred to, reported, or used in CME/CE in support or justification of a patient care recommendation must conform to the generally accepted standards of experimental design, data collection, and analysis.

    Unapproved Uses of Drugs/Devices: In accordance with requirements of the FDA, the audience is advised that information presented in this continuing medical education activity may contain references to unlabeled or unapproved uses of drugs or devices.  Please refer to the FDA approved package insert for each drug/device for full prescribing/utilization information.

  • System Requirements

    Our site requires a computer, tablet, or mobile device and a connection to the Internet. For best results, a high-speed Internet connection is recommended (DSL/Cable/Fibre). We also recommend using the latest version of your favorite browser to ensure compliance with W3C standards, such as Chrome, Safari, Firefox, or Microsoft Edge.

  • Publication Dates

    Release Date:

    Expiration Date:

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Details
Presenters
Comments
  • Overview

    In a “how I do it” clinical commentary, Dr. Jamile Shammo and Dr. Ilene Weitz share their real-world experience in the diagnosis and management of PNH in special patient populations. This case-based activity includes clinical scenarios and treatment strategies to improve patient outcomes. 

  • Provider(s)/Educational Partner(s)

    Sponsored by Rush University Medical Center and the Academy for Continued Healthcare Learning (ACHL).

  • Commercial Support

    Supported by educational grants from Alexion Pharmaceuticals, Inc and Apellis Pharmaceutical, Inc. 

  • Learning Objectives

    Upon completion of this activity, participants will be able to:

    • Discuss real-world experience in diagnosing and treating PNH in special patient populations
    • Formulate personalized treatment strategies considerate of patient risks, characteristics, complications, and preferences
    • Discuss coordination of care and clinical strategies amongst specialists to improve patient outcomes
  • Target Audience

    This educational activity is designed for hematologists, oncologists, pediatricians, OB/GYNs, and the multidisciplinary healthcare team who are involved in the care of patients with PNH.

  • Method of Participation

    This activity will take approximately 60 minutes to complete. To receive credit, participants are required to complete the pretest, view this internet enduring activity and complete the posttest and evaluation. To receive credit, 60% must be achieved on the posttest. A certificate will be immediately available. There is no fee to participate in the activity or for the generation of the certificate.

    For questions, contact Karen Catino at kcatino@achlcme.org

  • Accreditation and Credit Designation Statements

    In support of improving patient care, Rush University Medical Center is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC), to provide continuing education for the healthcare team.

    This activity is being presented without bias and with commercial support.

    Rush University Medical Center designates this internet enduring activity for a maximum of one (1) AMA PRA Category 1 Credit™. Physicians should claim only credit commensurate with the extent of their participation in the activity.

    Rush University Medical Center designates this internet enduring activity for a maximum of one (1) nursing contact hour.

  • Disclosure of Conflicts of Interest

    Disclosure Policy:
    As a provider of continuing education, Rush University Medical Center requires everyone who has the ability to control or influence the content of an educational activity to disclose information about all of their financial relationships with ineligible companies within the prior 24 months.  There is no minimum financial threshold; individuals must disclose all financial relationships, regardless of the amount, with ineligible companies.  Individuals must disclose regardless of their view of the relevance of the relationship to the education.  Mechanisms are in place to identify and mitigate any potential conflicts of interest prior to the start of the activity. 

    The following financial relationships have been disclosed:

    Ilene Weitz, MD 
    Sources of Funding for Research:
    Consulting Agreements: Apellis Pharmaceutical, Inc., Norvartic, BioCryst Pharmaceuticals, Inc.
    Speakers' Bureau: Alexion Pharmaceuticals, Inc

    Discussion of Off-Label, Investigational, or Experimental Drug/Device Use: Potential use of eculizumab, ravulizumab, and pegcetacoplan during pregnancy; investigational therapies for the treatment of PNH: ABP 959, SB12, BCD-148, crovalimab, SKY59, RO7112689, tesidolumab, LFG316, pozelimab, REGN3918, zilucoplan, RA101495, nomacopan, VA576, coversin, cemdisiran, ALN-CC5, danicopan, ACH-4471, BCX9930, iptacopan, LNP023

    Jamile Shammo, MD
    Sources of Funding for Research: Abbvie, Alexion Pharmaceuticals, Inc., AstraZeneca , Bristol Meyers Squibb, Incyte, CTI BioPharma, Kartos Therapeutics, Novartis, Stemline Therapeutics, Inc.,
    Consulting Agreements: Alexion Pharmaceuticals, Inc., Apellis Pharmaceutical, Inc., Bristol Meyers Squibb, Incyte, Novartis, Sanofi, Takeda
    Stockholder: Abbvie, Baxter, Takeda
    Speakers' Bureau: Alexion Pharmaceuticals, Inc., Bristol Meyers Squibb, Incyte, Sanofi
    Other: DSMC for Apellis Pharmaceutical, Inc., NS Pharma, Inc. 

    Discussion of Off-Label, Investigational, or Experimental Drug/Device Use: Potential use of eculizumab, ravulizumab, and pegcetacoplan during pregnancy; investigational therapies for the treatment of PNH: ABP 959, SB12, BCD-148, crovalimab, SKY59, RO7112689, tesidolumab, LFG316, pozelimab, REGN3918, zilucoplan, RA101495, nomacopan, VA576, coversin, cemdisiran, ALN-CC5, danicopan, ACH-4471, BCX9930, iptacopan, LNP023 

    Staff and Reviewer Disclosures
    ACHL and Rush University Medical Center staff members and others involved with the planning, development, and review of the content for this activity have no relevant financial relationship(s) with ineligible companies to disclose.

  • Disclaimer

    The content for this activity was developed independently of the commercial supporter. All materials are included with permission. The opinions expressed are those of the faculty and are not to be construed as those of the publisher or grantor.

    This educational activity was planned and produced in accordance with the ACCME Standards for Integrity and Independence in Accredited Continuing Education. Recommendations involving clinical medicine in a continuing medical education (CME/CE) activity must be based on evidence that is accepted within the profession of medicine as adequate justification for their indications and contraindications in the care of patients. All scientific research referred to, reported, or used in CME/CE in support or justification of a patient care recommendation must conform to the generally accepted standards of experimental design, data collection, and analysis.

    Unapproved Uses of Drugs/Devices: In accordance with requirements of the FDA, the audience is advised that information presented in this continuing medical education activity may contain references to unlabeled or unapproved uses of drugs or devices.  Please refer to the FDA approved package insert for each drug/device for full prescribing/utilization information.

  • System Requirements

    Our site requires a computer, tablet, or mobile device and a connection to the Internet. For best results, a high-speed Internet connection is recommended (DSL/Cable/Fibre). We also recommend using the latest version of your favorite browser to ensure compliance with W3C standards, such as Chrome, Safari, Firefox, or Microsoft Edge.

  • Publication Dates

    Release Date:

    Expiration Date:

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Schedule18 Jan 2022
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