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Diagnosis and Management of Primary Hyperparathyroidism

This CME online publication reviews the diagnosis and management of patients with primary hyperparathyroidism.

Available credits: 0.50

Time to complete: 30 minutes


Valid until:

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  • Overview

    CME Information

    Thomas J. Weber, MD
    Associate Professor of Medicine
    Division of Endocrinology, Metabolism and Nutrition
    Duke University Medical Center
    Durham, NC

    Activity Planners
    Christie Avraamides, PhD
    Clinical Content Manager
    Baltimore, MD

    Lisa R. Rinehart, MS, ELS
    Director, Editorial Services
    Baltimore, MD

    Amy Sison
    Director of Continuing Medical Education
    Baltimore, MD

    Katherine Stevens-Favorite, PhD
    Montpelier, VT

    Activity Overview
    This CME online publication reviews the diagnosis and management of patients with primary hyperparathyroidism (PHPT). It explores guideline-based approaches for assessing and managing patients with asymptomatic PHPT, including a discussion on clinical presentation, evaluation for asymptomatic PHPT, and surgical and medical management.

    Learning Objectives
    Upon completion, participants should be able to:

    • Identify patients with primary hyperparathyroidism
    • Understand the clinical indications for surgical referral in patients with primary hyperparathyroidism
    • Understand medical treatment options for patients with primary hyperparathyroidism

    Target Audience
    This activity is intended for physicians, nurse practitioners, physician assistants, nurses, and pharmacists.

    Statement of Need
    Primary hyperparathyroidism (PHPT) is the most common hypercalcemic disorder, present in 1% of the general adult population. This disorder can have broad physiologic effects, including reduced bone density, nephrolithiasis, cardiovascular dysfunction, and sometimes neurologic symptoms. For many years, PHPT was diagnosed by the presentation of these symptoms, most commonly renal calculi and/or osteoporosis with fractures. However, the broad implementation of biochemical panels in routine care has uncovered PHPT in patients who are generally asymptomatic or who have vague, unrecognized symptoms that may still affect quality of life. This publication is designed to help clinicians identify and manage patients with asymptomatic PHPT. 

    Providership Statement
    Co-provided by Med-IQ® and the Duke University Health System Department of Clinical Education and Professional Development.


    Accreditation/Designation Statements
    Med-IQ is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. Med-IQ designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

    Others: Nurse practitioners, physician assistants, and other healthcare professionals who successfully complete the activity will receive a Statement of Participation indicating the maximum credits available.

    Medium/Method of Participation
    This CME activity consists of a 0.5-credit online publication. To receive credit, read the introductory CME material, read the publication, and complete the evaluation, attestation, and post-test, answering at least 70% of the post-test questions correctly.

    Original Release Date: December 23, 2015
    Rerelease Date: January 31, 2017
    Expiration Date: January 30, 2018
    Estimated Time to Complete This Activity: 30 minutes

    The evaluation, attestation, and post-test may be accessed by clicking the “Take Post-Test” tab above.

    Disclosure Policy
    Med-IQ requires any person in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines "relevant financial relationships" as those in any amount occurring within the past 12 months, including those of a spouse/life partner, that could create a conflict of interest (COI). Individuals who refuse to disclose will not be permitted to contribute to this CME activity in any way. Med-IQ has policies in place that will identify and resolve COIs prior to this educational activity. Med-IQ also requires faculty to disclose discussions of investigational products or unlabeled/unapproved uses of drugs or devices regulated by the US Food and Drug Administration.

    Disclosure Statement
    The content of this activity has been peer reviewed and has been approved for compliance. The faculty and contributors have indicated the following financial relationships, which have been resolved through an established COI resolution process, and have stated that these reported relationships will not have any impact on their ability to give an unbiased presentation.

    Thomas J. Weber, MD
    Consulting fees/advisory boards: Ultragenyx Pharmaceutical
    Contracted research: Ultragenyx Pharmaceutical

    Katherine Stevens-Favorite, PhD
    Consulting fees/advisory boards: Leading BioSciences

    The peer reviewers and other activity planners have no financial relationships to disclose.

    Statement of Evidence-Based Content
    Educational activities that assist physicians in carrying out their professional responsibilities more effectively and efficiently are consistent with the ACCME definition of continuing medical education (CME). As an ACCME-accredited provider of CME, it is the policy of Med-IQ to review and ensure that all the content and any recommendations, treatments, and manners of practicing medicine in CME activities are scientifically based, valid, and relevant to the practice of medicine. Med-IQ is responsible for validating the content of the CME activities it provides. Specifically, (1) all recommendations addressing the medical care of patients must be based on evidence that is scientifically sound and recognized as such within the profession; (2) all scientific research referred to, reported, or used in CME in support or justification of a patient care recommendation must conform to generally accepted standards of experimental design, data collection, and analysis.

    Med-IQ is not liable for any decision made or action taken in reliance upon the information provided through this activity.

    Contact Information
    For CME-related questions or comments about this activity, please contact Med-IQ. Call (toll-free) 866 858 7434 or e-mail

    Hardware/Software Requirements
    ReachMD requires a computer, tablet or mobile device and a connection to the Internet. For best results, a high-speed Internet connection is recommended (DSL/cable). We also recommend using the latest version of your favorite browser to ensure compliance with W3C standards, such as Internet Explorer, Microsoft Edge, Chrome, Firefox or Safari. Users accustomed to IE8/IE9/IE10 are advised to update their browsers for the best experience.

    Microsoft Internet Explorer 11.0 or later

    Mozilla Firefox - latest version

    Google Chrome - latest version

    Apple Safari - latest version

    PDF Viewer
    Adobe Acrobat Reader® or Adobe Reader

    Adobe Flash Player
    Adobe Flash Player 9 or later

    For technical support, go to 

    ADA Statement
    Med-IQ fully complies with the legal requirements of the ADA and the rules and regulations thereof. If any participant in this educational activity is in need of accommodations, please contact Med-IQ at 443 543 5200.

    The information provided through this activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options of a specific patient’s medical condition.

    Privacy Policy

    © 2017 Duke University Health System and Med-IQ®. All rights reserved.

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