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Cystic Fibrosis: The Essential Role of Pancreatic Enzyme Replacement Therapy in Patient Care

Approximately 85-90% of patients with Cystic Fibrosis suffer from pancreatic insufficiency since birth, which significantly complicates the disease.

Available credits: 0.25

Time to complete: 15 minutes


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  • Overview

    Approximately 85-90% of patients with Cystic Fibrosis suffer from pancreatic insufficiency since birth, which significantly complicates the disease and adversely affects both quality of life and life expectancy.  Join Professor Suzanne Michele, registered dietitian, as she discusses supplemental enzymes and their role in the health of persons who have CF, the barriers to adherence with pancreatic enzyme replacement therapy, and how pancreatic enzyme replacement therapy is dosed in patients with CF.

  • Disclosure of Conflicts of Interest

    In accordance with the ACCME Standards for Commercial Support, The Omnia-Prova Education Collaborative (TOPEC) requires that individuals in a position to control the content of an educational activity disclose all relevant financial relationships with any commercial interest. TOPEC resolves all conflicts of interest to ensure independence, objectivity, balance, and scientific rigor in all its educational programs.

    Suzanne Michel, MPH, RD, LDN
    Clinical Assistant Professor
    Medical University of South Carolina
    Charleston, SC

    Faculty’s disclosure
    Professor Michel receives consulting fees from AbbVie. 


    • Sean T. Barrett has nothing to disclose.
    • Colleen Braun has nothing to disclose.
    • Barry A. Fiedel, PhD has nothing to disclose
    • Kia K. Gray, MPH has nothing to disclose.
    • Nick Lombardi has disclosed he owns stock in Vertex.
    • Brian P. McDonough, MD, FAAFP, has nothing to disclose. 
    • John J. Russell, MD receives consulting fees from GALDERMA and speaker bureau fees from Sanofi Pasteur.
    • Jennifer Spear Smith, PhD has nothing to disclose.

    The PIM planners and managers, Trace Hutchison, PharmD, Samantha Mattiucci, PharmD, CHCP, Judi Smelker-Mitchek, MBA, MSN, RN, and Jan Schultz, MSN, RN, CHCP have nothing to disclose.

  • Learning Objectives

    After participating in this educational activity, participants should be better able to:

    • Discuss supplemental enzymes and their role in the health of persons who have CF.
    • Identify barriers to adherence with pancreatic enzyme replacement therapy in patients with cystic fibrosis and how such barriers may be effectively addressed.
    • Explain how pancreatic enzyme replacement therapy is dosed in patients with cystic fibrosis.
  • Target Audience

    This activity is designed to meet the educational needs of primary care physicians, pulmonologists, registered nurses, nurse practitioners, dieticians, respiratory therapists and health care professionals associated with cystic fibrosis accredited care centers.

  • Accreditation and Credit Designation Statements

    Accreditation and Credit Designation Statements:
    The Omnia-Prova Education Collaborative, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

    The Omnia-Prova Education Collaborative, Inc. designates this enduring material for a maximum of .25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

    Continuing Nursing Education
    The Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.  This educational activity for 0.5 contact hour(s) is provided by the Postgraduate Institute for Medicine.

    For Nurses:
    If you wish to receive acknowledgment for completing this activity, please complete the evaluation on  On the navigation menu, click on “Find Post-test/Evaluation by Course” and search by course ID 12098.  Upon registering and successfully completing the activity evaluation, your certificate will be made available immediately. 

  • Provider(s)/Educational Partner(s)

    Prova Education designs educational activities based on evidence-based medicine, needs and gaps analyses, learner feedback, and more. Its mission is to serve as an innovative and relevant resource for clinical content and educational interventions across a broad spectrum of specialties.

    Prova Education

    Co-provided by Postgraduate Institute for Medicine and Prova.

  • Commercial Support

    This activity is supported by an independent educational grant from AbbVie.

  • Disclaimer

    The views and opinions expressed in this educational activity are those of the faculty and do not necessarily represent the views of TOPEC and Prova Education. This presentation is not intended to define an exclusive course of patient management; the participant should use his/her clinical judgment, knowledge, experience and diagnostic skills in applying or adopting for professional use any of the information provided herein. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients’ conditions and possible contraindications or dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities. Links to other sites may be provided as additional sources of information. Once you elect to link to a site outside of Prova Education you are subject to the terms and conditions of use, including copyright and licensing restriction, of that site.

    Reproduction Prohibited
    Reproduction of this material is not permitted without written permission from the copyright owner.

  • System Requirements

    Our site requires a computer, tablet or mobile device and a connection to the Internet. For best results, a high-speed Internet connection is recommended (DSL/cable). We also recommend using the latest version of your favorite browser to ensure compliance with W3C standards, such as Internet Explorer, Microsoft Edge, Chrome, Firefox or Safari. Users accustomed to IE8, IE9 IE10 are advised to update their browsers for the best experience."

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